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曾朝辉,何林,赵金亮,梁剑.强腰祛痛汤联合西药治疗腰椎间盘突出症经皮椎间孔镜髓核摘除术后残留神经症状疗效观察[J].湖南中医药大学学报英文版,2019,39(12):1521-1524.[Click to copy
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| 强腰祛痛汤联合西药治疗腰椎间盘突出症经皮椎间孔镜髓核摘除术后残留神经症状疗效观察 |
| 曾朝辉,何林,赵金亮,梁剑 |
| (湖南中医药高等专科学校附属第一医院, 湖南 株洲 412000) |
| 摘要: |
| 目的 研究腰椎间盘突出症患者经皮椎间孔镜髓核摘除术后采用强腰祛痛汤联合甲钴胺、塞来昔布治疗的临床效果及对患者残留神经症状的影响。方法 将84例经皮椎间孔镜髓核摘除术治疗后残留神经症状的腰椎间盘突出症患者按随机数字表法分为两组各42例。对照组、观察组分别采用甲钴胺+塞来昔布以及甲钴胺+塞来昔布+强腰祛痛汤治疗。观察两组患者治疗效果、腰椎功能、疼痛状况、生活质量以及不良反应情况。结果 观察组治疗总有效率（92.86%）高于对照组（83.33%），差异有统计学意义（P<0.05）。治疗后两组腰椎功能均较治疗前有改善（P<0.05），且观察组改善优于对照组（P<0.05）。治疗后两组视觉模拟疼痛评分（visual analogue score，VAS）、日常生活量表（activity of dailyLiving scale，ADL）评分均较治疗前改善（P<0.05），且观察组上述评分均优于对照组（P<0.05）。观察组不良反应发生率（19.05%）与对照组（14.29%）比较差异无统计学意义（P>0.05）。结论 强腰祛痛汤联合甲钴胺和塞来昔布对腰椎间盘突出症经皮椎间孔镜髓核摘除术后残留神经症状的患者具有较好疗效，能明显改善患者残留神经症状，缓解患者疼痛，提高患者生活质量，安全性较高，值得临床应用及推广。 |
| 关键词: 腰椎间盘突出症 强腰祛痛汤 甲钴胺 塞来昔布 经皮椎间孔镜髓核摘除术 |
| DOI：10.3969/j.issn.1674-070X.2019.12.022 |
| Received:April 08, 2019 |
| 基金项目: |
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| Efficacy Observation on Qiangyao Qutong Decoction Combined with Western Medicine in the Residual Neurological Signs of Patients with Lumbar Disc Herniation after Percutaneous Transforaminal Endoscopic Discectomy |
| ZENG Chaohui,HE Lin,ZHAO Jinliang,LIANG Jian |
| (The First Affiliated Hospital of Hunan College of Traditional Chinese Medicine, Zhuzhou, Hunan 412000, China) |
| Abstract: |
| Objective To study the effects of Qiangyao Qutong Decoction plus mecobalamine and celecoxib in in the residual neurological signs of patients with lumbar disc herniation (LDH) after percutaneous transforaminal endoscopic discectomy (PTED). Methods A total of 84 patients with LDH underwent PTED were randomly assigned to 2 groups, with 42 cases in each group. The control group was served with mecobalamine and celecoxib; on the basis of the former, the observation group was served with Qiangyao Qutong Decoction. The therapeutic effect, lumbar-vertebral function, pain degree, quality of life and adverse reactions of the 2 groups were observed. Results The total effective rate in the observation group (92.86%) was higher than the control group (83.33%), and the difference was statistically significant (P<0.05). After treatment, the lumbar function of the 2 groups were improved than before (P<0.05), and the improvement of the observation group was better than the control group (P<0.05). After treatment, the VAS (visual analogue scale) and ADL (activity of daily living) scores of the 2 groups were improved than before (P<0.05), and the above scores of the observation group was better than the control group (P<0.05). There was no significant difference in the incidence of the adverse reactions in the observation group (19.05%) and the control group (14.29%). Conclusion The combined therapy of Qiangyao Qutong Decoction, mecobalamine and celecoxib in the treatment of the residual neurological signs of patients with LDH after PTED has better curative effects, which can dramatically improve the residual neurological signs, relieve the pain, and increase the quality of life, with higher clinical safety. It is worthy of clinical application and promotion. |
| Key words: lumbar disc herniation Qiangyao Qutong Decoction mecobalamine celecoxib percutaneous transforaminal endoscopic discectomy |
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