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徐淼, 刘泽豪, 刘铜华, 秦灵灵, 王海焱, 吕翠岩, 高明.从熵流模型视角探析运用中医八法治疗肾性水肿[J].湖南中医药大学学报英文版,2026,46(2):335-341.[Click to copy
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| 从熵流模型视角探析运用中医八法治疗肾性水肿 |
| 徐淼,刘泽豪,刘铜华,秦灵灵,王海焱,吕翠岩,高明 |
| (北京中医药大学, 北京 100029;首都医科大学附属北京中医医院, 北京 100010;日本武库川女子大学, 日本 兵库 663-8558) |
| 摘要: |
| 肾性水肿是慢性肾脏病常见的临床表现之一，观其中医病因，多为患者肾脏功能受损，机体水液代谢失衡，发病过程中涉及肺、脾、三焦等多脏气化失调。随着中医理论的不断发展，中医八法的内涵不断完善，程钟龄于《医学心悟·医门八法》中提出“汗、和、下、消、吐、清、温、补”八法体系。当代医家贤达，善用八法之妙，法随证立，方从法出，临床疗效确切。本文以熵流模型为理论框架，探析肾性水肿的病理本质：肾功能减退导致尿素、肌酐等高熵代谢废物蓄积，引发机体系统熵值显著增高，即从有序走向无序。中医八法通过多途径调控熵流平衡以治疗水肿，汗、吐、下法直接导邪外出，清除熵积；清、消法瓦解湿热瘀结，瓦解熵聚；和法调和气机，阻断熵传；温、补法则振奋阳气、培补根本，增强机体抗熵能力。由此可见，八法共同通过对能量代谢与水液输布的调节，直接干预熵的产生、流动与清除过程，推动系统从无序向有序转化。本文系统阐述八法如何通过调控熵流治疗肾性水肿，旨在将中医整体观转化为可量化的数理模型，为中西医整合治疗提供理论依据与实践路径。 |
| 关键词: 中医八法 肾性水肿 治法 熵 熵流模型 |
| DOI：10.3969/j.issn.1674-070X.2026.02.016 |
| Received:August 03, 2025 |
| 基金项目:科技部国家重点研发计划政府间国际科技创新合作重点专项项目(2021YFE0106300);教育部、科研部高等学校学科创新引智计划项目(B20055)。 |
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| Application of the eight therapeutic methods of TCM for renal edema from the perspective of the entropy flow model |
| XU Miao, LIU Zehao, LIU Tonghua, QIN Lingling, WANG Haiyan, LYU Cuiyan, GAO Ming |
| (Beijing University of Chinese Medicine, Beijing 100029, China;Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China;Mukogawa Women's University, Hyogo Prefecture 663-8558, Japan) |
| Abstract: |
| Renal edema is one of the common clinical manifestations of chronic kidney disease. From the perspective of TCM, its etiopathogy is largely attributed to impaired renal function in patients, leading to an imbalance in the body's fluid metabolism. Its pathogenesis involves disordered qi transformation of multiple zang-fu organs, including the lung, spleen and sanjiao. With the continuous development of TCM theory, the connotation of the eight therapeutic methods of TCM has been constantly improved. CHENG Zhongling, in the chapter "The Eight Therapeutic Methods" of Yi Xue Xin Wu (Medical Revelations), proposed the system of the eight therapeutic methods:sweating, harmonizing, draining downward, reducing, vomiting, clearing, warming, and tonifying. Contemporary distinguished TCM physicians are adept at the exquisite application of these eight methods, formulating therapies in accordance with patterns and prescribing formulas based on therapies, which yields definite clinical curative effects. Taking the entropy flow model as the theoretical framework, this paper explores the pathological essence of renal edema:renal insufficiency leads to the accumulation of high-entropy metabolic wastes such as urea and creatinine, resulting in a significant increase in the entropy value of the body's system, that is, a shift from order to disorder. The eight therapeutic methods of TCM treat the edema by regulating the balance of entropy flow through multiple approaches:methods of sweating, vomiting, and draining downward directly expel pathogenic factors, eliminating entropy accumulation; clearing and reducing methods break down damp-heat and stasis bindings, dissolving entropy aggregation; harmonizing method regulates qi movement, blocking entropy transmission; and warming and tonifying methods invigorate yang qi and consolidate the root, enhancing the body's anti-entropy capacity. Thus, the eight therapeutic methods collectively intervene directly in the generation, flow, and clearance of entropy by modulating energy metabolism and fluid distribution, driving the system's transition from disorder towards order. This paper systematically elaborates on how the eight therapeutic methods treat renal edema by regulating entropy flow, aiming to transform the holistic view of TCM into a quantifiable mathematical model, and provide a theoretical basis and practical approach for the integrated treatment of TCM and Western medicine. |
| Key words: eight therapeutic methods of TCM renal edema therapeutic methods entropy entropy flow model |
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