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吴东海, 吴婧, 周玮, 王平杰, 龚晶, 徐易琳, 夏新华.当归补血汤的药学、药理作用及临床应用研究进展[J].湖南中医药大学学报英文版,2025,45(3):577-582.[Click to copy
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| 当归补血汤的药学、药理作用及临床应用研究进展 |
| 吴东海,吴婧,周玮,王平杰,龚晶,徐易琳,夏新华 |
| (湖南中医药大学药学院, 湖南 长沙 410208;湖南省药品审核查验中心, 湖南 长沙 410001) |
| 摘要: |
| 当归补血汤系古代经典名方，由黄芪和当归两味中药组成，具有益气补血的功效，主要用于治疗气血两虚证。其应用形式多样（如汤剂、颗粒剂、丸剂、口服液剂），可通过不同的机制发挥促进造血功能、心血管保护、调节免疫、抗肿瘤和抗纤维化等方面的药理作用，临床用于改善贫血、妇科调理、改善肿瘤化疗后骨髓抑制、骨折术后康复及治疗糖尿病肾病等方面，均具有良好的疗效。从药学、药理作用、临床应用3个方面对当归补血汤最新研究进展进行系统的归纳和综述，以期为其进一步研究与应用提供借鉴。 |
| 关键词: 当归补血汤 黄芪 当归 药学 药理作用 临床应用 研究进展 |
| DOI：10.3969/j.issn.1674-070X.2025.03.030 |
| Received:October 08, 2024 |
| 基金项目:湖南省重点研发计划项目（2018SK2114）。 |
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| Research progress on pharmacy, pharmacological actions, and clinical applications of Danggui Buxue Decoction |
| WU Donghai, WU Jing, ZHOU Wei, WANG Pingjie, GONG Jing, XU Yilin, XIA Xinhua |
| (School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Drug Inspection Center, Changsha, Hunan 410001, China) |
| Abstract: |
| Danggui Buxue Decoction is an ancient classic formula, consisting of two Chinese medicines, Huangqi (Radix Astragali) and Danggui (Radix Angelicae Sinensis), with the effects of tonifying qi and supplementing blood, and is mainly used to treat qi and blood deficiency. It is available in various dosage forms such as decoction, granules, pills, and oral liquid, exerting pharmacological actions through various mechanisms in promoting hematopoietic function, cardiovascular protection, immune regulation, anti-tumor, and anti-fibrosis. Clinically, it has demonstrated good efficacy in reducing anemia, regulating gynecological health, relieving chemotherapy-induced bone marrow suppression, aiding recovery after fracture surgery, and alleviating diabetic nephropathy. This paper systematically summarizes and reviews the latest research progress on Danggui Buxue Decoction from three aspects of pharmacy, pharmacology action, and clinical applications, aiming to provide a reference for its further research and application. |
| Key words: Danggui Buxue Decoction Huangqi (Radix Astragali) Danggui (Radix Angelicae Sinensis) pharmacy pharmacological action clinical application research progress |
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