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王林华, 卢敏, 段航, 刘鑫, 邝高艳, 赵益, 周晟.胫骨横向骨搬移微创导板技术联合桃红四物汤治疗糖尿病足溃疡的疗效分析[J].湖南中医药大学学报英文版,2024,44(9):1646-1652.[Click to copy
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| 胫骨横向骨搬移微创导板技术联合桃红四物汤治疗糖尿病足溃疡的疗效分析 |
| 王林华,卢敏,段航,刘鑫,邝高艳,赵益,周晟 |
| (湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学, 湖南 长沙 410208) |
| 摘要: |
| 目的 观察胫骨横向骨搬移微创导板技术联合桃红四物汤治疗糖尿病足溃疡（diabetic foot ulcer, DFU）的疗效。方法 选取自2021年1月至2022年12月在湖南中医药大学第一附属医院四肢关节科拟进行胫骨横向骨搬移手术的50例DFU患者为研究对象，随机分为观察组与对照组，各25例。对照组采用胫骨横向骨搬移微创导板技术结合常规基础治疗；观察组在对照组基础上，术后第1天开始服用桃红四物汤，均连续治疗4周。比较治疗前和治疗后3个月两组患者的疼痛视觉模拟量表（visual analogue scale, VAS）评分、患肢皮肤温度、10 g尼龙丝检查评分、踝肱指数以及溃疡创面面积、愈合时间，评估临床疗效。结果 治疗3个月后，观察组临床有效率为92%，高于对照组的76%（P＜0.05）；观察组溃疡创面愈合时间较对照组明显缩短（P＜0.05）；两组患者的VAS评分、患肢皮肤温度、10 g尼龙丝检查评分、踝肱指数均较治疗前明显改善（P＜0.05），且观察组上述各项指标较对照组改善更明显（P＜0.05）。结论 胫骨横向骨搬移微创导板技术联合桃红四物汤治疗DFU的临床疗效显著，创伤小，创面愈合快，可明显缓解患肢疼痛，加速溃疡创面修复。 |
| 关键词: 糖尿病足溃疡 胫骨横向骨搬移 微创 导板 桃红四物汤 微循环 瘀血阻络 |
| DOI：10.3969/j.issn.1674-070X.2024.09.014 |
| Received:January 15, 2024 |
| 基金项目:湖南省自然科学基金青年基金项目（2017JJ3244）；湖南中医药大学中医学一流学科开放基金重点课题（2021ZYX08）；长沙市自然科学基金项目（kq2208207）。 |
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| Curative efficacy analysis of transverse tibial bone transport minimally invasive guide plate technique combined with Taohong Siwu Decoction in treating diabetic foot ulcer |
| WANG Linhua, LU Min, DUAN Hang, LIU Xin, KUANG Gaoyan, ZHAO Yi, ZHOU Sheng |
| (The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective To observe the curative efficacy of transverse tibial bone transport minimally invasive guide plate technique combined with Taohong Siwu Decoction (THSWD) in treating diabetic foot ulcer (DFU). Methods Fifty patients with DFU who were scheduled to undergo transverse tibial bone transport surgery in the Department of Limbs and Joints, the First Hospital of Hunan University of Chinese Medicine from January 2021 to December 2022 were selected as the research subjects and randomly divided into observation and control groups, with 25 cases in each group. The control group was treated with minimally invasive guide plate technology combined with conventional basic treatment, while the observation group was additionally given THSWD starting from the first day after operation, with continuous treatment for four weeks in both groups. The pain visual analogue scale (VAS), skin temperature of the affected limb, 10 g monofilament test score, ankle brachial index, and the ulcer wound area and healing time were compared between the two groups before and three months after treatment to evaluate clinical efficacy. Results After three months of treatment, the clinical effective rate of the observation group was 92%, which was higher than the 76% of the control group (P＜0.05); the healing time of ulcer wounds in the observation group was significantly shortened compared to the control group, with statistically significant difference (P＜0.05); the VAS, affected limb skin temperature, 10 g monofilament test score, and ankle brachial index of patients in both groups were significantly improved compared with those before treatment (P＜0.05), and the above indexes in the observation group were improved more significantly than those in the control group (P＜0.05). Conclusion Transverse tibial bone transport minimally invasive guide plate technique combined with THSWD demonstrates significant clinical efficacy in treating DFU, with small wound and fast wound healing, which can obviously relieve the pain in affected limb and accelerate ulcer wound repair. |
| Key words: diabetic foot ulcer transverse tibial bone transport minimally invasive guide plate Taohong Siwu Decoction microcirculation blood stasis blocking collaterals |
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