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熊家青,徐基平,李逵,吴泳蓉,黄晓蒂,田莎,吴若霞,田雪飞.中医药辨证调控骨髓造血微环境的机制研究[J].湖南中医药大学学报英文版,2020,40(11):1421-1426.[Click to copy
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| 中医药辨证调控骨髓造血微环境的机制研究 |
| 熊家青,徐基平,李逵,吴泳蓉,黄晓蒂,田莎,吴若霞,田雪飞 |
| (湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学附属衡阳中医医院, 湖南 衡阳 421001;湖南中医药大学中西医结合学院, 湖南 长沙 410208) |
| 摘要: |
| 由于多种原因所导致的骨髓造血功能低下是临床上常见的问题，目前西医尚缺乏有效的治疗方法，而中医药在提升骨髓造血功能方面展现出了独特优势。本文通过检索本领域相关文献，并进行总结归纳，发现中医药多从肾、脾、气、血、毒等方面来辨证论治骨髓造血功能低下，具体作用机制可能与其调控骨髓造血微环境中的细胞因子或细胞结构有关。 |
| 关键词: 中医药 骨髓造血 造血微环境 机制 |
| DOI：10.3969/j.issn.1674-070X.2020.11.024 |
| Received:April 20, 2020 |
| 基金项目:湖南省教育厅优秀青年项目（19B423）；湖南省自然科学基金青年基金项目（2020JJ5440）；国家自然科学基金项目（81603603，81473617）；湖南省教育厅开放平台基金项目（16K066）；湖南省科技计划项目（2017SK50310）；湖南中医药大学中西医结合一流学科开放基金（2018ZXYJH28，2018ZXYJH03，2018ZXYJH04）；湖南省研究科研创新项（CX20190541）。 |
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| Study on the Mechanism of Traditional Chinese Medicine Regulating the Hematopoietic Microenvironment of Bone Marrow Based on Syndrome Differentiation |
| XIONG Jiaqing,XU Jiping,LI Kui,WU Yongrong,HUANG Xiaodi,TIAN Sha,WU Ruoxia,TIAN Xuefei |
| (The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hengyang Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Chinese Medicine, Hengyang, Hunan 421001, China;School of Integrative Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| The low hematopoietic function of bone marrow caused by various reasons is a common problem in clinical practice, but currently western medicine is still lack of effective treatment. Traditional Chinese medicine in the improvement of bone marrow hematopoietic function has shown a unique advantage. By searching the relevant literature in this field, this paper summarized and found that traditional Chinese medicine mainly treats the hematopoietic dysfunction of bone marrow based on syndrome differentiation from kidney, spleen, Qi, blood and toxin, etc. The specific mechanism of action may be related to the regulation of cytokines or cell composition in the hematopoietic microenvironment of bone marrow. |
| Key words: traditional Chinese medicine bone marrow hematopoiesis mechanism |
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