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周亚敏,胡玉珍,唐洁,夏伯候,李亚梅,林丽美,廖端芳.天然多糖对心血管系统保护作用的研究进展[J].湖南中医药大学学报英文版,2016,36(12):78-84.[Click to copy
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| 天然多糖对心血管系统保护作用的研究进展 |
| 周亚敏,胡玉珍,唐洁,夏伯候,李亚梅,林丽美,廖端芳 |
| (湖南中医药大学, 湖南 长沙 410208;湖南省中药不良成分快速检测及脱除工程技术研究中心, 湖南 长沙 410208;中药有毒物质防控技术湖南省工程实验室, 湖南 长沙 410208) |
| 摘要: |
| 多糖（Polysaccharide）广泛存在于动物、植物、微生物中，它们是一类结构复杂的天然高分子化合物，大多是有益于人体健康的活性物质。大量的药理和临床研究表明，天然多糖具有多种药理活性，尤其具有降血糖、降血压、降血脂、抗凝血、抑制血管平滑肌增生等独特作用，可改善人体微循环，用于预防和治疗高脂血症、动脉粥样硬化、冠心病等心血管疾病。本文综述了近年来相关文献中多糖对心血管系统保护作用的研究概况，以期为开发有益于心血管保护作用的多糖保健功能食品与天然无毒副药物提供依据。 |
| 关键词: 多糖 降血糖 降血压 抗凝血 心血管疾病 |
| DOI：10.3969/j.issn.1674-070X.2016.12.020 |
| Received:December 31, 2015 |
| 基金项目:科技部“重大新药创制”（2013ZX09201019）；教育部高等学校博士学科点专项科研基金（20124323120004）；湖南省自然科学基金（13JJ4089）；长沙市重点科技计划（k1406039-31）；湖湘青年科技创新创业平台人才项目（2013）；湖南省十二五重点学科药学学科资助。 |
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| Advance in the Protective Effects of Natural Polysaccharides on Cardiovascular System |
| ZHOU Yamin,HU Yuzhen,TANG Jie,XIA Bohou,LI Yamei,LIN Limei,LIAO Duanfang |
| (School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Engineering Center for Rapid Test and Removal of Toxic and Harmful Substances in Chinese Medicine, Changsha, Hunan 410208, China;Hunan Engineering Laboratory for Prevention and Control Technology of Toxic Substances in Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Polysaccharide widely exists in animals, plants, microorganisms, which is a kind of complex structure of natural polymer compound, mostly are active substances beneficial to human body health. A lot of pharmacology and clinical studies have shown that natural polysaccharide has many pharmacological activities, especially hpyerglycemic, hypotensive, hypolipidemic, anticoagulant, inhibition of vascular smooth muscle hyperplasia. It can improve the body circulation and prevent hyperlipidemia, atherosclerosis, coronary heart disease and other cardiovascular diseases. This paper reviews the research progress about natural polysaccharides in the study of protective effect on cardiovascular system in recent years, to provide references for developing the medicines with no toxic and side effects and healthy foods in preventing and treating cardiovascular diseases. |
| Key words: polysaccharide hpyerglycemic hypotensive anticoagulation cardiovascular disease |
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