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陈菁,冯国湘.艾灸盒温灸对阳虚体质者症状及血清cAMP/cGMP比值的影响[J].湖南中医药大学学报英文版,2016,36(6):64-67.[Click to copy
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| 艾灸盒温灸对阳虚体质者症状及血清cAMP/cGMP比值的影响 |
| 陈菁,冯国湘 |
| (湘南学院, 湖南 郴州 423000;湖南中医药大学第二附属医院, 湖南 长沙 410005) |
| 摘要: |
| 目的 观察艾灸盒温灸疗法对阳虚体质者症状及血清环磷酸腺苷（cAMP）/环磷酸鸟苷（cGMP）比值的影响，探究阳虚体质与cAMP/cGMP比值的相关性。方法 将90例阳虚体质受试者随机分为灸盒组、参附液组、肾气丸组，每组30例，3组均以7 d为1个疗程，连用4个疗程。根据治疗后受试者阳虚质判定评分量表的得分情况评价疗效，同时观察治疗前后血清cAMP/cGMP比值变化情况。结果 治疗后，3组受试者阳虚体质转化分均较前显著下降（P<0.01），灸盒组下降程度高于参附液组和肾气丸组（P<0.05）；3组受试者血清cAMP/cGMP比值均较前下降（P<0.05），其中灸盒组下降幅度最高（P<0.05）；灸盒组总有效率为53.3%，参附液组总有效率为43.3%；，肾气丸组总有效率40.0%，3组整体疗效相当（P>0.05）。结论 艾灸盒温灸能显著改善阳虚体质，cAMP/cGMP与阳虚体质存在一定的相关性。 |
| 关键词: 阳虚体质 温灸 艾灸盒 环磷酸腺苷 环磷酸鸟苷 |
| DOI：10.3969/j.issn.1674-070X.2016.06.016 |
| Received:October 15, 2015 |
| 基金项目:湖南省科学技术厅科技计划项目（2013SK3906）。 |
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| Effects of the Warming Box-Moxibustion on the Symptom and the Ratio of Serum cAMP/cGMP in the Subjects with Yang Deficiency Constitution |
| CHEN Jing,FNEG Guoxiang |
| (Xiangnan University, Chenzhou, Hunan 423000, China;The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410005, China) |
| Abstract: |
| Objective To observe the warming box-moxibustion's effect on symptoms of Yang deficiency constitution and investigate its correlation with on cAMP/cGMP ratio. Methods A total of 90 Yang deficiency constitution subjects were assigned to warming box-moxibustion group, Shenfu liquid group and Shenqi pill group, 30 cases in each group, the groups were given four 7-day courses consecutively. Then the scores of yang deficiency CCMQ (Constitution in Chinese Medicine Questionnaire) were evaluated and the change of cAMP/cGMP ratio before and after treatment was observed. Results The yang deficiency CCMQ scores of the three groups were decreased after treatment (P<0.01). The decrement of yang deficiency CCMQ scores in box-moxibustion group was higher than those in Shenfu liquid group and Jinkuishenqi pill group(P<0.05). The cAMP/cGMP ratio in serum of the three groups reduce significantly after treatment (P<0.05). The cAMP/cGMP ratio in box-moxibustion group has the highest extent of reducing (P<0.05). After treatment, the total effective rate in box-moxibustion group was 53.3%, while in Shenfu liquild group was 43.3%, and Shenqi pill group was 40.0%; while comparing the overall curative effect of the three groups, there was no statistically significant difference (P>0.05). Conclusion Warming box-moxibustion can significantly improve Yang deficiency constitution, and there was some correlation between cAMP/cGMP and yang deficiency constitution. |
| Key words: Yang-deficiency constitution warming moxibustion box-moxibustion cAMP cGMP |
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