| 引用本文: |
韩驰, 周佳, 孙贵炎, 管天护, 刘书源, 李源, 赵用.基于“痞坚之处，必有伏阳”理论探讨高尿酸血症致痛风石的防治[J].湖南中医药大学学报,2026,46(7):1488-1495[点击复制] |
|
| |
|
|
| 本文已被：浏览 61次 下载 48次 |
| 基于“痞坚之处，必有伏阳”理论探讨高尿酸血症致痛风石的防治 |
| 韩驰,周佳,孙贵炎,管天护,刘书源,李源,赵用 |
| (辽宁中医药大学, 辽宁 沈阳 110847;辽宁中医药大学附属第二医院, 辽宁 沈阳 110034) |
| 摘要: |
| 痛风石（TG）是痛风慢性进展的特征性病理产物，高尿酸血症持续进展是其核心诱因，临床易致关节畸形、肾损伤等，现代医学已明确其形成与尿酸盐结晶沉积、慢性炎症介导损伤及组织纤维化重塑密切相关，但中医领域对其病机传变规律与辨证防治体系尚缺乏系统梳理。“痞坚之处，必有伏阳”是中医阐释有形实邪郁遏阳气的经典病机理论，其核心病机与高尿酸血症向痛风石演进的病理过程高度契合。本文基于该病机理论，梳理伏阳失固、伏阳化热、伏阳凝浊、伏阳结聚四阶段分期病机，分别对应尿酸代谢紊乱、急性炎症暴发、滑膜增生损伤、TG形成的病理进程，提出温阳补虚、疏阳散火、助阳化浊、扶阳散结四阶段分期防治，为中医药全程干预TG形成提供新的理论依据与诊疗思路。 |
| 关键词: 痛风性关节炎|痛风石|痞坚|伏阳|分期防治|中医药 |
| DOI：10.3969/j.issn.1674-070X.2026.07.024 |
| 投稿时间：2026-01-24 |
| 基金项目:沈阳市科学技术计划项目（24-214-3-180）；辽宁省名中医传承工作室项目（辽中医药综合字〔2024〕19号）。 |
|
| Prevention and treatment of hyperuricemia-induced tophaceous gout based on the theory of "Where there is a painful hard mass, there must be latent yang" |
| HAN Chi, ZHOU Jia, SUN Guiyan, GUAN Tianhu, LIU Shuyuan, LI Yuan, ZHAO Yong |
| (Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning 110847, China;The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning 110034, China) |
| Abstract: |
| Tophaceous gout(TG) are characteristic pathological products of chronic gout, with persistent hyperuricemia serving as the core predisposing factor. Clinically, they tend to cause joint deformity, renal injury, and other complications. Modern medicine has clearly established that their formation is closely associated with urate crystal deposition, chronic inflammation-mediated damage, and tissue fibrosis remodeling. However, the pathogenesis evolution patterns and the corresponding system of pattern differentiation, prevention, and treatment of this condition in TCM have not yet been systematically elucidated. The theory of "Where there is a painful hard mass, there must be latent yang" is a classical TCM pathogenesis theory that elucidates how tangible pathogenic factors obstruct yang qi. Its core pathogenesis is highly consistent with the pathological progression from hyperuricemia to gouty tophi. Based on this theory, this paper systematically delineates the four-stage pathogenesis of latent yang: loss of consolidation, transformation into heat, condensation into turbidity, and aggregation into mass, corresponding respectively to the pathological processes of uric acid metabolic disorder, acute inflammatory flare-up, synovial hyperplasia and injury, and tophus TG formation. Accordingly, a four-stage-based prevention and treatment strategy is proposed: warming yang and supplementing deficiency, disper-sing latent yang and draining fire, assisting yang in transforming turbidity, and supporting yang and dissipating masses. This provides a new theoretical basis and diagnostic-therapeutic framework for TCM intervention throughout the entire course of tophus TG formation. |
| Key words: gouty arthritis|tophaceous gout|painful hard mass|latent yang|stage-based prevention and treatment|Chinese medicine |
|
二维码（扫一下试试看！） |
|
|
|
|
