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唐诗, 游卉, 邢艺璇, 刘未艾, 熊桀, 莫蕙, 尤昭玲.“养胎三部曲”在IVF-ET中的临证应用[J].湖南中医药大学学报英文版,2025,45(9):1613-1618.[Click to copy
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| “养胎三部曲”在IVF-ET中的临证应用 |
| 唐诗,游卉,邢艺璇,刘未艾,熊桀,莫蕙,尤昭玲 |
| (湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学第二附属医院, 湖南 长沙 410005;湖南中医药大学, 湖南 长沙 410208;澳门科技大学, 中国 澳门 999078) |
| 摘要: |
| 在辅助生殖技术中，减少反复胚胎种植失败及复发性流产的发生是改善助孕结局的关键。全国名中医尤昭玲教授立足胎、孕、产的生理以及脏腑功能，创新性提出“养胎三部曲”。“养胎三部曲”指导体外受精-胚胎移植（IVF-ET）保胎过程中医全过程管理：着床期助孕，以健脾纳胎为主，兼顾补肾；孕早期固胎，以补肾固胎为主，兼顾健脾；孕中晚期育胎，脾肾并重。尤昭玲教授提出以通补并用为原则，脾肾并举，因时制宜，药膳结合，以提高IVF-ET胚胎种植率、活产率，减少不良妊娠风险，为解决种植失败、妊娠丢失等临床生殖难题提供思路。 |
| 关键词: 体外受精-胚胎移植 不良妊娠 养胎三部曲 补肾固胎 健脾纳胎 尤昭玲 |
| DOI：10.3969/j.issn.1674-070X.2025.09.004 |
| Received:June 16, 2025 |
| 基金项目:国家中医药管理局“尤昭玲全国名中医传承工作室”建设项目(国中医药办人教函[2022]5号); 湖南省科学技术厅重点领域研发计划项目(2023SK2050,2025JK2111); 湖南省卫生健康科研计划项目(20258008); 湖南省自然科学基金项目(2025JJ80972); 国家中医药管理局中医药古籍文献和特色技术传承专项项目(GZY-KJS-2021-035)。 |
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| Clinical application of the Three-Stage Fetal-Nurturing Protocol in in vitro fertilization-embryo transfer |
| TANG Shi, YOU Hui, XING Yixuan, LIU Wei'ai, XIONG Jie, MO Hui, YOU Zhaoling |
| (The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;The Second Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410005, China;Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Macau University of Science and Technology, Macau, 999078, China) |
| Abstract: |
| In assisted reproductive technology, reducing recurrent implantation failure and pregnancy loss is pivotal to improving conception outcomes. Professor YOU Zhaoling, the national famous TCM physician, grounding her approach in the physiology of conception, gestation and parturition together with visceral function, innovatively proposes the "Three-Stage FetalNurturing Protocol." This protocol guides Chinese medicine whole-course management for pregnancy maintenance after in vitro fertilization-embryo transfer（IVF-ET）: during implantation period, assist conception by strengthening the spleen to secure the embryo, while secondarily tonifying the kidney; in early pregnancy, consolidate gestation by primarily tonifying the kidney to stabilize the fetus, while secondarily strengthening the spleen; in mid-and late pregnancy, nourish the fetus by simultaneously strengthening spleen and kidney. Professor YOU advocates the combined use of unblocking and tonifying methods, simultaneously regulating the spleen and kidney, tailoring measures to various stages, and integrating Chinese medicines with dietary therapy. This strategy aims to increase embryo implantation rates and live birth rates in IVF-ET while reducing the risks of adverse pregnancy outcomes, offering insights for clinical reproductive challenges such as implantation failure and pregnancy loss. |
| Key words: in vitro fertilization-embryo transfer adverse pregnancy outcomes Three-Stage Fetal-Nurturing Protocol tonifying kidney to stabilize fetus strengthening the spleen to secure the embryo YOU Zhaoling |
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