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陈曦, 郝晓凤, 谢立科.基于玄府理论辨治原发性开角型青光眼[J].湖南中医药大学学报英文版,2025,45(8):1495-1499.[Click to copy
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| 基于玄府理论辨治原发性开角型青光眼 |
| 陈曦,郝晓凤,谢立科 |
| (中国中医科学院眼科医院, 北京 100040) |
| 摘要: |
| 原发性开角型青光眼（POAG）属于中医学“青风内障”范畴。刘完素的玄府理论突破了《内经》认为玄府为汗孔的局限，构建了中医微观病机框架。基于玄府理论辨治POAG，谢立科教授认为玄府失常是贯穿于POAG全程的根本原因，神水壅滞是POAG发病的基础。将POAG发展过程分为病起期、病进期、病重期，主张病起期治以疏肝清热、通利玄府，使用丹栀逍遥散加减；病进期治以益气活血、开通玄府，使用补阳还五汤加减；病重期治以滋肝补肾、益精养玄，使用杞菊地黄丸加减。保证玄府通利，促进神水流通，进而防治本病。 |
| 关键词: 原发性开角型青光眼 玄府 神水 辨证论治 理论探讨 |
| DOI：10.3969/j.issn.1674-070X.2025.08.014 |
| Received:April 22, 2025 |
| 基金项目:中国中医科学院眼科医院高水平中医医院揭榜挂帅项目(GSP4-02-2,GSP4-02-3);北京市自然科学基金面上项目(7242263);首都卫生发展科研专项重点公关项目(2020-1-4181);国家卫生健康委员会老龄司项目(2023-234) |
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| Pattern identification and treatment of primary open-angle glaucoma based on the theory of mysterious mansion |
| CHEN Xi, HAO Xiaofeng, XIE Like |
| (Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China) |
| Abstract: |
| Primary open-angle glaucoma（POAG） is classified within the category of "bluish glaucoma" in Chinese medicine（CM）. LIU Wansu’s theory of mysterious mansion Xuanfu broke through the limitation in the Huang Di Nei Jing（Huangdi’s Classic of Medicine） that regarded the mysterious mansion merely as sweat pores, establishing a CM micro-level pathological framework.Based on the theory of mysterious mansion, Professor XIE Like holds that the dysfunction of mysterious mansion is the fundamental cause throughout the entire course of POAG, and the stagnation of aqueous humour is the pathological basis of the disease onset.The progression of POAG can be divided into three distinct stages: the initial stage, the progressive stage, and the advanced stage.In the initial stage of the disease, treatment focuses on soothing the liver and clearing heat to dredge the mysterious mansion, and the modified Danzhi Xiaoyao Powder can be used. In the progressive stage, the therapeutic principle is tonifying qi and circulating blood to unblock the mysterious mansion, and the modified Buyang Huanwu Decoction is applied. In the advanced stage, the focus is on nourishing the liver and kidney and enriching the essence to support the function of the mysterious mansion, and the modified Qiju Dihuang Pill is employed. The core therapeutic goal is to ensure the unimpeded function of the mysterious mansion and facilitate the normal circulation of aqueous humour, thereby achieving both prevention and management of POAG. |
| Key words: primary open-angle glaucoma mysterious mansion aqueous humour pattern identification and treatment theoretical discussion |
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