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Quote : 杨虹, 姚玙, 霍勤.霍勤教授基于目玄府-络脉理论辨治前部缺血性视神经病变[J].湖南中医药大学学报英文版,2026,46(2):405-410.[Click to copy ]
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霍勤教授基于目玄府-络脉理论辨治前部缺血性视神经病变
杨虹,姚玙,霍勤
(河南中医药大学第一附属医院眼科, 河南 郑州 451452;河南中医药大学, 河南 郑州 450046)
摘要:
    前部缺血性视神经病变(AION)是营养视神经的微血管发生循环障碍,致视神经缺血缺氧的眼部病变。目前其发病机制尚未明确,临床亦缺乏规范化的治疗方案。目玄府和目络脉作为眼部微观结构和功能的核心单元,是眼部气血津液循行的通道。霍勤教授基于目玄府-络脉理论阐述AION的发病机制,认为该病是由“玄府闭塞-气血瘀滞-目络瘀阻”所致。故在辨证论治时,应围绕“开玄府-通气血-畅络脉”进行,采用急性期“辛味风药开通玄府”与萎缩期“虫藤类药补虚通络”的分期治疗策略。附验案一则,以期为临床诊治AION提供理论依据和实践路径。
关键词:  前部缺血性视神经病变  目玄府  目络脉  分期论治  辛味风药  虫藤类药
DOI:10.3969/j.issn.1674-070X.2026.02.027
Received:September 18, 2025  
基金项目:河南省中医药科学研究专项课题(2022ZY1028)。
Professor HUO Qin's approach to differentiating and treating anterior ischemic optic neuropathy based on the theory of ocular mysterious mansion-collaterals
YANG Hong, YAO Yu, HUO Qin
(Department of Ophthalmology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan 451452, China;Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China)
Abstract:
    Anterior ischemic optic neuropathy (AION) is an ocular lesion caused by circulatory impairment of the microvessels that nourish the optic nerve, resulting in ischemia and hypoxia. Currently, its pathogenesis remains unclear, and standardized clinical treatment protocols are lacking. The ocular mysterious mansion and collaterals, serving as the core microstructural and functional units of the eyes, constitute the pathways for the circulation of qi, blood, and body fluids. Based on the theory of ocular mysterious mansion-collaterals, Professor HUO Qin expounds that the pathogenesis of AION is attributable to the "obstruction of mysterious mansion-qi stagnation and blood stasis-obstruction of ocular collaterals". Therefore, the treatment based on pattern identification should focus on the principle of "opening mysterious mansion-promoting the circulation of qi and blood-unblocking collaterals." And a stage-based treatment strategy is recommended, with "pungent-flavoured and wind-dispersing medicinals to open mysterious mansion" in the acute stage and "insect and vine medicinals to supplement deficiency and unblock collaterals" in the atrophy stage. A verified medical record is included to provide theoretical basis and practical approaches for the clinical diagnosis and treatment of AION.
Key words:  anterior ischemic optic neuropathy  ocular mysterious mansion  ocular collaterals  stage-based treatment  pungent-flavored and wind-dispersing medicinals  worm and vine medicinals
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