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张文青, 王贤文, 叶飞, 容建策, 刘洁, 田道法, 范婧莹.基于“一气周流”理论的“轴-轮-流”模型探讨耳聋病理机制及诊疗策略[J].湖南中医药大学学报英文版,2026,46(2):323-328.[Click to copy
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| 基于“一气周流”理论的“轴-轮-流”模型探讨耳聋病理机制及诊疗策略 |
| 张文青,王贤文,叶飞,容建策,刘洁,田道法,范婧莹 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007;中山市人民医院, 广东 中山 528445;中山市黄圃人民医院, 广东 中山 528429) |
| 摘要: |
| 文章以“一气周流”理论为指导，通过梳理中气如轴，四维如轮，周流不息的理论渊源，提出以脾胃为枢纽，肝、心、肺、肾为四轮、气血津液周流为动力的“轴-轮-流”整体动态模型。并进一步阐释耳聋病机与中轴失运、轮辐失调、周流阻滞的密切关系，以及“轴-轮-流”模型与内耳微循环障碍、神经传导异常及氧化应激等机制的关联性，确立以斡旋中轴、疏利四轮、通络复聪为核心的多层次诊疗策略。通过融合中医整体观与现代分子生物学证据，本文可为耳聋诊疗提供理论创新与临床实践参考，凸显中医整体调控的独特优势。 |
| 关键词: “一气周流” “轴-轮-流”模型 中轴失运 轮辐失调 周流阻滞 耳聋 |
| DOI：10.3969/j.issn.1674-070X.2026.02.014 |
| Received:October 12, 2025 |
| 基金项目:国家自然科学基金项目(82505683);湖南省自然科学基金项目(2024JJ6343);湖南省中医药管理局资助项目(B2024006);湖南省卫生健康委员会卫生健康科研项目(20257618,20253881);湖南省研究生创新项目(CX20251197)。 |
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| Pathological mechanism and diagnostic-therapeutic strategies for deafness based on the “axis-wheel-flow” model of “circumfluence of qi” theory |
| ZHANG Wenqing, WANG Xianwen, YE Fei, RONG Jiance, LIU Jie, TIAN Daofa, FAN Jingying |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Zhongshan City People's Hospital, Zhongshan, Guangdong 528445, China;Huangpu People's Hospital of Zhongshan City, Zhongshan, Guangdong 528429, China) |
| Abstract: |
| Guided by the "circumfluence of qi" theory, this article traces the theoretical origins of the concepts "qi of the middle jiao as the axis and four dimensions as the wheels," which operate in an endless cycle. It proposes an integrated dynamic "axis-wheel-flow" model in which the spleen and stomach serve as the pivotal axis, the liver, heart, lung, and kidney act as the four wheels, and the circumfluence of qi, blood, and body fluids provides the driving force. It further explains the close relationship between the pathogenesis of deafness and the malfunction of the central axis, imbalance of the wheel spokes, and obstruction of circumfluence. The article also explores the connections between the "axis-wheel-flow" model and mechanisms such as inner ear microcirculation disorders, abnormal nerve conduction, and oxidative stress. Based on this, it establishes a multi-level diagnostic and therapeutic strategy centered on "regulating the central axis," smoothing the four wheels, and unblocking collaterals to restore hearing. By integrating the holistic perspective of Chinese medicine with modern molecular biological evidence, this paper aims to provide theoretical innovation and clinical practice references for the diagnosis and treatment of deafness, highlighting the unique advantages of holistic regulation in Chinese medicine. |
| Key words: circumfluence of qi "axis-wheel-flow" model malfunction of the central axis imbalance of the wheel spokes obstruction of circumfluence deafness |
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