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周欣滢, 孙丹, 朱文浩.基于《黄帝内经》肉苛病探讨吉兰-巴雷综合征的诊治[J].湖南中医药大学学报英文版,2026,46(1):139-142.[Click to copy
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| 基于《黄帝内经》肉苛病探讨吉兰-巴雷综合征的诊治 |
| 周欣滢,孙丹,朱文浩 |
| (山东中医药大学, 山东 济南 250355;淄博市中医医院, 山东 淄博 255399) |
| 摘要: |
| 吉兰-巴雷综合征（GBS）是一种以四肢急性弛缓性麻痹为主要症状的周围神经免疫性疾病，其临床表现与《黄帝内经》肉苛病之“不仁且不用”高度吻合。本文基于古代医家对肉苛病的论述，结合临床实践，系统探讨GBS的中医病因病机及辨治思路。GBS的基本病机为营卫俱虚，临床常兼寒邪、瘀血为患，治疗上以调补营卫为主，兼顾温经散寒、活血祛瘀之法，方选黄芪桂枝五物汤为主，临证可配伍当归四逆汤、麻黄细辛附子汤、桃红四物汤。基于上述分析，本文旨在为GBS的中医临床诊治提供理论依据与实践参考。 |
| 关键词: 肉苛病 吉兰-巴雷综合征 营卫俱虚 黄芪桂枝五物汤 辨治经验 |
| DOI：10.3969/j.issn.1674-070X.2026.01.019 |
| Received:October 08, 2025 |
| 基金项目:第五批全国中医临床优秀人才研修项目（国中医药人教函〔2022〕1号）。 |
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| Exploring the diagnosis and treatment of Guillain-Barré syndrome based on the rouke disease in Huang Di Nei Jing (Huangdi's Classic of Medicine) |
| ZHOU Xinying, SUN Dan, ZHU Wenhao |
| (Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China;Zibo Hospital of Traditional Chinese Medicine, Zibo, Shandong 255399, China) |
| Abstract: |
| Guillain-Barré syndrome (GBS) is an immune-mediated peripheral neuropathy characterized by acute flaccid paralysis of the limbs. Its clinical manifestations are highly consistent with the patterns of "numbness and motor impairment" in the rouke disease (somatic stiffness disease) of Huang Di Nei Jing (Huangdi's Classic of Medicine). Based on the ancient physicians' discussions on rouke disease and combined with clinical practice, this paper systematically explores TCM etiological factors, pathogenesis, differentiation, and treatment ideas of GBS. The fundamental pathogenesis of GBS is the deficiency of both Ying-nutrient qi and Wei-defensive qi, clinically often accompanied by pathogenic cold and blood stasis. The therapeutic principle is mainly to regulate and tonify Ying-nutrient qi and Wei-defensive qi, supplemented by methods of warming meridians and dissipating cold, circulating blood and transforming stasis. Huangqi Guizhi Wuwu Decoction is selected as the primary formula, and can be combined with Danggui Sini Decoction, Mahuang Xixin Fuzi Decoction, and Taohong Siwu Decoction according to clinical patterns. This study aims to provide theoretical basis and practical reference for the clinical diagnosis and treatment of GBS in TCM. |
| Key words: rouke disease Guillain-Barré syndrome deficiency of both Ying-nutrient qi and Wei-defensive qi Huangqi Guizhi Wuwu Decoction differentiation and treatment experience |
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