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韩晴, 刘畅.从“火与元气不两立”探讨激素依赖性皮炎病机与治疗思路[J].湖南中医药大学学报英文版,2025,45(12):2385-2390.[Click to copy
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| 从“火与元气不两立”探讨激素依赖性皮炎病机与治疗思路 |
| 韩晴,刘畅 |
| (黑龙江中医药大学研究生院, 黑龙江 哈尔滨 150040;黑龙江中医药大学附属第一医院, 黑龙江 哈尔滨 150040) |
| 摘要: |
| 激素依赖性皮炎（HDD）是长期外用激素类制剂引发的皮肤疾病，以皮肤潮红、丘疹、灼热肿痛为基本表现。激素在中医学中属于“药毒”范畴，其性燥烈，一方面致脾胃受损、肺肾失和，使元气生成不足（本虚）；另一方面，药毒内蕴化火，与湿热搏结，致使阴火稽留（标实），最终形成“火胜气负”的本虚标实证。治疗上应标本兼顾，治本通过健运脾胃、调理肺肾、预培其损以恢复气血津液输布，治标针对药毒化火、湿热蕴蒸、虚火内扰等病理环节施以凉血降火、清除湿热、制约虚火即“治火三法”。通过培元与治火并举，使阴火衰而元气复，为中医辨治HDD提供经典理论指导与新的治疗思路。 |
| 关键词: 火与元气不两立 激素依赖性皮炎 阴火 元气亏虚 药毒 |
| DOI：10.3969/j.issn.1674-070X.2025.12.020 |
| Received:July 22, 2025 |
| 基金项目:黑龙江中医药经典普及化专项课题（ZYW2024-048）。 |
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| Pathogenesis and treatment of hormone-dependent dermatitis based on theory of "yin fire and Yuan-primordial qi are intrinsically opposed" |
| HAN Qing, LIU Chang |
| (The Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China) |
| Abstract: |
| Hormone-dependent dermatitis (HDD) is an inflammatory skin disorder induced by prolonged topical corticosteroid use, characterized by skin redness, papules, burning sensation, swelling, and pain. In Chinese medicine, corticosteroids fall under the category of "medicinal toxin." Their dry and potent nature can damage the spleen and stomach and disrupt the harmony between the lung and kidney, leading to insufficient generation of Yuan-primordial qi (root deficiency). Concurrently, the internal retention of this medicinal toxin transforms into fire, which intertwines with dampness-heat, resulting in the lingering of yin fire (a deficiency fire resulting from weakness of the spleen and stomach and insufficient Yuan-primordial qi) (branch excess). This ultimately gives rise to a pattern of root deficiency and branch excess, manifesting as "yin fire prevailing over Yuan-primordial qi." Therapeutic intervention should address both the branch and the root manifestations. The root treatment focuses on restoring the distribution of qi, blood, and body fluids by strengthening the spleen and stomach and regulating the lung and kidney to preemptively repairing their damage. The branch treatment targets the pathological links of medicinal toxin transforming into fire, dampness-heat accumulation, and deficiency fire internal disturbance by applying the "Three Methods for Treating Fire": cooling blood and reducing fire, clearing dampness-heat, and restraining deficiency fire. By concurrently cultivating Yuan-primordial qi and treating pathological fire, yin fire is subdued while Yuan-primordial qi is restored. This approach provides a classical theoretical framework and novel therapeutic insights for TCM diagnosis and treatment of HDD. |
| Key words: yin fire and Yuan-primordial qi are intrinsically opposed hormone-dependent dermatitis yin fire Yuan-primordial qi deficiency medicinal toxin |
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