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Quote : 任祥, 杨松, 孟灵, 刘妮杰, 蒋学余, 张泓.子午流注视角下肩袖损伤夜间疼痛的昼夜节律机制与针灸治疗策略[J].湖南中医药大学学报英文版,2025,45(11):2130-2135.[Click to copy ]
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子午流注视角下肩袖损伤夜间疼痛的昼夜节律机制与针灸治疗策略
任祥,杨松,孟灵,刘妮杰,蒋学余,张泓
(湖南中医药大学, 湖南 长沙 410208;湖南中医药大学附属岳阳医院, 湖南 岳阳 414000)
摘要:
    肩袖损伤是一种以肩部疼痛、活动受限及夜间疼痛为特征的常见肌腱疾病,严重影响患者睡眠与生活质量。近年研究发现,其夜间疼痛受生物钟昼夜节律调控,夜间加重与内分泌节律失调、炎症因子蓄积、中枢敏化、睡姿等因素密切相关。中医子午流注理论亦强调人体气血运行具有时辰节律性,与生物钟昼夜节律在时间医学层面形成呼应。本文通过揭示肩袖损伤夜间疼痛的时间规律,提出基于子午流注理论的择时针灸治疗策略,为改善肩袖损伤患者的治疗效果和生活质量提供新思路和新方法。
关键词:  肩袖损伤  子午流注  昼夜节律  夜间疼痛  择时治疗  针灸
DOI:10.3969/j.issn.1674-070X.2025.11.014
Received:July 17, 2025  
基金项目:湖南省自然科学基金项目(2024JJ7603); 湖南省卫生健康委科研课题(D202304079413); 湖南中医药大学校院联合基金项目(2023XYLH065);湖南中医药大学教改课题(2023-LHJG016)。
Circadian rhythm mechanism and acupuncture treatment strategies for nocturnal pain in rotator cuff injury based on the midnight-noon ebb-flow theory
REN Xiang, YANG Song, MENG Ling, LIU Nijie, JIANG Xueyu, ZHANG Hong
(Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Yueyang Hospital Affiliated with Hunan University of Chinese Medicine, Yueyang, Hunan 414000, China)
Abstract:
    Rotator cuff injury(RCI) is a common tendinopathy characterized by shoulder pain, limited range of motion, and nocturnal pain, which significantly impairs patients’ sleep and quality of life. Recent studies have found that nocturnal pain in RCI is regulated by the circadian rhythm of the biological clock, and its exacerbation at night is closely associated with factors such as endocrine rhythm disruption, accumulation of inflammatory factors, central sensitization, and sleeping posture. The midnight-noon ebb-flow theory in Chinese medicine also emphasizes that the circulation of qi and blood follows a temporal rhythm, which resonates with the biological circadian rhythm in the context of chronomedicine. By revealing the temporal pattern of nocturnal pain in RCI, this paper proposes timing acupuncture treatment strategies based on the midnight-noon ebb-flow theory, providing new insights and approaches to improve therapeutic outcomes and quality of life for patients with RCI.
Key words:  rotator cuff injury  midnight-noon ebb-flow  circadian rhythm  nocturnal pain  timing treatment  acupuncture
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