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李亚楠, 陈志刚, 李楠楠, 张新宁, 王丽晔, 张含, 田浩.基于脑髓-脑气-脑神-脑窍论治多系统萎缩[J].湖南中医药大学学报英文版,2025,45(5):921-926.[Click to copy
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| 基于脑髓-脑气-脑神-脑窍论治多系统萎缩 |
| 李亚楠,陈志刚,李楠楠,张新宁,王丽晔,张含,田浩 |
| (北京中医药大学东方医院, 北京 100078;北京中医药大学, 北京 100029;西安市中医医院, 陕西 西安 710021) |
| 摘要: |
| 从脑髓-脑气-脑神-脑窍角度论治多系统萎缩，认为脑髓消减是多系统萎缩病机之本，脑气逆乱是病理表现，脑神失用是病进之由，脑窍被扰是标实表现。根据脑髓-脑气-脑神-脑窍四者之轻重精准施治，以益肾填精补脑髓为治疗之本，根据疾病的分期及症状侧重不同，可酌情佐以调补脑气畅气机、安养神志复神机、化痰祛瘀开窍闭，起到标本兼顾的效果。附验案一则，以飨同道。 |
| 关键词: 多系统萎缩 脑髓 脑气 脑神 脑窍 |
| DOI：10.3969/j.issn.1674-070X.2025.05.020 |
| Received:October 13, 2024 |
| 基金项目:国家自然科学基金项目（82174328）。 |
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| Treating multiple system atrophy based on the theory of brain marrow-brain qi-brain spirit-brain orifice |
| LI Ya'nan, CHEN Zhigang, LI Nannan, ZHANG Xinning, WANG Liye, ZHANG Han, TIAN Hao |
| (Oriental Hospital of Beijing University of Chinese Medicine, Beijing 100078, China;Beijing University of Chinese Medicine, Beijing 100029, China;Xi'an Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi 710021, China) |
| Abstract: |
| The treatment of multiple system atrophy (MSA) is discussed from the perspectives of brain marrow-brain qi-brain spirit-brain orifice. It is believed that the depletion of brain marrow constitutes the root of pathogenetic mechanism of MSA, the disorder of brain qi represents its pathological manifestation, the dysfunction of brain spirit serves as the driving force behind disease progression, and the disturbance of brain orifice presents the excess manifestation. Precise treatment strategies are tailored according to the relative severity of the four aspects of brain marrow-brain qi-brain spirit-brain orifice. The fundamental therapeutic approach focuses on tonifying the kidneys and replenishing essence to nourish the brain marrow. Depending on the disease stage and the predominant symptoms, adjunctive therapies may be employed, including regulating and tonifying brain qi to smooth qi movement, calming and nourishing the mind to restore functional activities of spirit, as well as resolving phlegm and eliminating blood stasis to open the blocked orifice. This approach aims to achieve a comprehensive effect that addresses both the root cause and the manifestations of the disease. A verified medical record is appended below for the reference and benefit of fellow practitioners. |
| Key words: multiple system atrophy brain marrow brain qi brain spirit brain orifice |
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