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李钟琳, 李玉, 贾晓薇, 唐雨时, 李城.从伏毒理论探析应用风药治疗结直肠癌[J].湖南中医药大学学报英文版,2024,44(11):2116-2120.[Click to copy
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| This paper
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| 从伏毒理论探析应用风药治疗结直肠癌 |
| 李钟琳,李玉,贾晓薇,唐雨时,李城 |
| (天津中医药大学中医学院, 天津 301617;天津市现代中医理论创新转化重点实验室, 天津 301617) |
| 摘要: |
| 结直肠癌是常见的消化系统恶性肿瘤，可归属于中医学“积聚”“脏毒”“肠风”等范畴。在病因上，结直肠癌发病可因外感所致，亦可因内伤引发；病机上，其特点为正虚伏毒，即以正气亏虚为本，以痰饮、湿浊、血瘀凝聚为标；病势上，其特点为隐伏、暴戾、暗耗、迁延不愈。通过探究伏毒理论，认为其与结直肠癌在病因、病机、病势特点上有较多相似之处。风药具有宣散透邪、疏肝行气、胜湿行散、活血消癥、搜风通络、扶正透散等功效，为结直肠癌的防治提供了新的研究思路与方法。 |
| 关键词: 伏毒 风药 积聚 结直肠癌 扶正祛邪 |
| DOI：10.3969/j.issn.1674－070X.2024.11.026 |
| Received:May 07, 2024 |
| 基金项目:国家自然科学基金项目（82305073）;天津市自然科学基金项目（22JCQNJC01290）;天津市教委科研计划项目（2021KJ135）。 |
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| Application of wind medicines in treating colorectal cancer based on the latent toxin theory |
| LI Zhonglin, LI Yu, JIA Xiaowei, TANG Yushi, LI Cheng |
| (School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;Tianjin Key Laboratory of Innovation and Transformation for Modern Chinese Medicine Theory, Tianjin 301617, China) |
| Abstract: |
| Colorectal cancer is a common malignant tumor of the digestive system, which can be classified into the categories of "abdominal masses", "anal abscess", and "intestinal wind (bloody stools)" in Chinese medicine. It can be caused by either exogenous pathogenic factors or endogenous ones. The characteristics of its pathogenesis can be summarized as latent toxins with a deficiency of healthy qi, where the root cause lies in the deficiency of healthy qi, and the manifestations include phlegm, fluid retention, turbid dampness, and blood stasis. As for the disease tendency, it is marked by latency, aggressiveness, gradual depletion, and a protracted course. Through exploring the latent toxin theory, it is believed that there are many similarities between this theory and colorectal cancer in terms of etiology, pathogenesis, and disease tendency. Therefore, the application of wind medicines (including wind-dispelling medicines and Chinese medicines possessing wind-like actions) offers new research ideas and approaches for the prevention and treatment of colorectal cancer, with effects such as dispersing pathogens, soothing the liver and circulating qi, dispelling dampness and dissipating stagnation, promoting blood circulation and resolving masses, removing wind and unblocking collaterals, and reinforcing healthy qi to eliminate pathogenic factors. |
| Key words: latent toxin wind medicines abdominal masses colorectal cancer reinforcing healthy qi to eliminate pathogenic factors |
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