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吴泠钰, 刘平安, 刘慧萍, 尤昭玲, 王桂云, 王凯玲, 杜玉, 唐璇.尤昭玲教授诊疗早发性卵巢功能不全患者IVF-ET中医辅助方案的构建与临证实践[J].湖南中医药大学学报英文版,2024,44(8):1523-1527.[Click to copy
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| 尤昭玲教授诊疗早发性卵巢功能不全患者IVF-ET中医辅助方案的构建与临证实践 |
| 吴泠钰,刘平安,刘慧萍,尤昭玲,王桂云,王凯玲,杜玉,唐璇 |
| (湖南中医药大学, 湖南 长沙 410208;湖南省卫生健康委员会, 湖南 长沙 410008;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 早发性卵巢功能不全（premature ovarian insufficiency, POI）是指女性在40岁之前出现性腺功能的减退，临床表现为继发性闭经、不孕，常伴有夜间睡眠过程中出汗、失眠、记忆力减退等围绝经期症状。本文主要介绍尤昭玲教授对患者行中医辅助IVF-ET论证思路及特色治疗。尤教授认为POI患者不孕的主要病因为肾元亏虚、血瘀致病，故在治疗上以固本培元、活血化瘀为主，并根据二期序贯与三期三法，采用尤氏“辨卵调泡八法”，妙用花药随证加减，同时佐以食疗巩固疗效。并附验案1则，以资佐证。 |
| 关键词: 原发性卵巢功能不全 尤昭玲 体外受精 胚胎移植术 二期序贯 三期三法 辨卵调泡 |
| DOI：10.3969/j.issn.1674-070X.2024.08.025 |
| Received:May 08, 2024 |
| 基金项目:国家级大学生创新创业计划训练项目（202110541042）；湖南省大学生创新创业计划训练项目（202110541042）；湖南省自然科学基金项目（2022JJ30035）；湖南省中医药科研计划项目重点项目（2021025）；湖南省教育厅科学研究重点项目（21A0233）；湖南省卫生健康委科研项目重点指导课题（202305017379）；湖南省卫生健康高层次人才重大科研专项项目（R2023168）。 |
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| Construction and clinical practice of IVF-ET TCM auxiliary program for diagnosing and treating patients with premature ovarian insufficiency by Professor YOU Zhaoling |
| WU Lingyu, LIU Ping'an, LIU Huiping, YOU Zhaoling, WANG Guiyun, WANG Kailing, DU Yu, TANG Xuan |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Health Commission, Changsha, Hunan 410008, China;The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Premature ovarian insufficiency (POI) refers to the decline of gonadal function in women before the age of 40, which is manifested clinically by secondary amenorrhea and infertility, accompanied with perimenopausal symptoms such as nocturnal sweating, insomnia, and memory loss. This paper mainly introduces Professor YOU Zhaoling's argumentation and characteristic treatment of IVF-ET assisted by TCM for patients with POI. Professor YOU believes that the main etiology of infertility in patients with POI is deficiency of kidney essence, and blood stasis, which can be mainly treated by strengthening the kidney, consolidating the basis, circulating blood, and transforming stasis. Based on sequential treatment in two phases of menstruation and three stages (downregulation stage, ovulation promotion stage, post-transplantation stage) with three corresponding methods (Chinese medicine conditioning, dietary aid, ear-points application and pressing), Professor YOU adopts her "eight methods for identifying and regulating follicles", skillfully using flower drugs with modifications made according to pattern identification, combined with food therapy to consolidate the curative effects. Furthermore, a verified medical record is attached for evidence. |
| Key words: primary ovarian insufficiency YOU Zhaoling in vitro fertilization embryo transfer sequential treatment in two phases of menstruation three stages with three corresponding methods identifying and regulating follicles |
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