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雷竣显, 周派, 彭俊, 田赛男, 彭清华.基于“肝-脑-目”轴探讨中医药论治干眼[J].湖南中医药大学学报英文版,2024,44(7):1308-1312.[Click to copy
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| 基于“肝-脑-目”轴探讨中医药论治干眼 |
| 雷竣显,周派,彭俊,田赛男,彭清华 |
| (湖南中医药大学, 湖南 长沙 410208;湖南省中医药防治眼耳鼻咽喉疾病与视功能保护工程技术研究中心, 湖南 长沙 410208) |
| 摘要: |
| “肝”“脑”“目”三者在生理及病理上相互联系，形成了“肝-脑-目”轴交互体系。其关系存在多向交互串扰，影响干眼的发生发展。应用脏腑辨证理论从生理和病理两个层面对“肝-脑-目”轴的内涵进行阐述，并提出“肝-脑-目”轴的3种失衡状态及其与干眼发病的关系，且肝、肾与目的关系为“肝-脑-目”轴理论之关键。提出清肝疏肝以畅“肝-脑-目”轴、益精生髓以充“肝-脑-目”轴、补肝肾阴以理“肝-脑-目”轴的中医药治疗干眼思路，以期为临床治疗干眼提供参考。 |
| 关键词: 干眼 “肝-脑-目”轴 脏腑辨证 肝肾阴虚 清肝疏肝 益精生髓 补肝肾阴 |
| DOI：10.3969/j.issn.1674-070X.2024.07.024 |
| Received:January 22, 2024 |
| 基金项目:国家中医药管理局人才支持项目——岐黄学者（国中医药人教函〔2022〕6号）；湖南省人才托举工程——年轻优秀科技人才培养计划项目（2023TJ-N25）；湖南省科技厅临床创新引导项目（2021SK51402）；湖南省教育厅科学研究项目（22C0191）。 |
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| Treatment of dry eyes with Chinese Medicine based on “liver-brain-eye” axis |
| LEI Junxian, ZHOU Pai, PENG Jun, TIAN Sainan, PENG Qinghua |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Engineering and Technological Research Center for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine and Protecting Visual Function, Changsha, Hunan 410208, China) |
| Abstract: |
| The "liver", "brain", and "eye" are intimately connected both physiologically and pathologically, constituting an interactive system known as the "liver-brain-eye" axis. This axis exhibits multi-directional interactions and crosstalk, influencing the onset and progression of dry eyes. This paper employs the theory of pattern identification of zang-fu organs to expound on the connotations of the "liver-brain-eye" axis from both physiological and pathological perspectives. It proposes three states of disequilibrium within the "liver-brain-eye" axis and their associations with the pathogenesis of dry eyes, emphasizing that the relationship among the liver, kidney, and eyes is pivotal to the "liver-brain-eye" axis theory. To offer ideas to dry-eye treatment as clinical references, this paper introduces the concepts of Chinese medicine: clearing and soothing the liver to harmonize the "liver-brain-eye" axis, tonifying essence and generating marrow to replenish the "liver-brain-eye" axis, and nourishing liver and kidney yin to regulate the "liver-brain-eye" axis. |
| Key words: dry eyes "liver-brain-eye" axis pattern identification of zang-fu organs yin deficiency of the liver and kidney clearing and soothing the liver tonifying essence and generating marrow nourishing liver and kidney yin |
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