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李宇翔,王彪,刘侃,陈亚,胡国恒.基于气味厚薄理论探析黄连减轻神经炎症的中医机制[J].湖南中医药大学学报英文版,2024,44(3):499-503.[Click to copy
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| 基于气味厚薄理论探析黄连减轻神经炎症的中医机制 |
| 李宇翔,王彪,刘侃,陈亚,胡国恒 |
| (湖南中医药大学第一中医临床学院, 湖南 长沙 410007;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 神经炎症几乎发生在所有中枢神经系统疾病的进展过程中，随着临床实践及科学研究的深入，发现黄连及以黄连为主要组成的中药复方对减轻神经炎症、改善疾病预后均有较好效果。基于对“气味厚薄”理论内容的梳理，阐明黄连具有“大苦大寒，味厚气薄”的作用特点，并论述黄连功效与神经炎症中医病机之间的关联，以及黄连通过清心、厚肠、坚肾阴3个方面起到减轻神经炎症的作用机制。 |
| 关键词: 神经炎症 黄连 气味厚薄 中枢神经系统疾病 心脑同治 肠脑同治 肾脑同治 |
| DOI：10.3969/j.issn.1674-070X.2024.03.024 |
| Received:October 02, 2023 |
| 基金项目:国家中医药管理局“全国名老中医药专家传承工作室”建设项目（国中医药人教函﹝2022﹞75号）；国家自然科学基金项目（81573941）；湖南省自然科学基金项目（2020JJ4476）；湖南省卫生健康委员会2020科研计划课题（20201617）；湖南省教育厅科学研究项目（20C1420）；湖南中医药大学校级研究生创新课题项目（2022CX143）。 |
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| Chinese medicine mechanism of Huanglian (Coptids Rhizoma) in alleviating neuroinflammation based on qi (yang) and flavor (yin) theory |
| LI Yuxiang,WANG Biao,LIU Kan,CHEN Ya,HU Guoheng |
| (The First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Neuroinflammation occurs in the progression of all central nervous system disease. With the deepening of clinical practice and scientific research, we found that Huanglian (Coptids Rhizoma) and the formulas mainly composed of Huanglian (Coptids Rhizoma) had good effects on relieving neuroinflammation and improving the prognosis of the disease. Based on qi (yang) and flavor (yin) theory, we clarified the characteristics of Huanglian (Coptids Rhizoma) as "extremely bitter and cold, strong flavor, and thin qi". We also identified its correlation with the pathogenesis of neuroinflammation in Chinese medicine, and its mechanism of relieving neuroinflammation through clearing the heart, nourishing intestines, and invigorating the kidney yin. |
| Key words: neuroinflammation Huanglian (Coptids Rhizoma) qi (yang) and flavor (yin) theory central nervous system disease same treatment for heart and brain same treatment for intestine and brain same treatment for kidney and brain |
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