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黄博,阮磊,王兰兰,薛惠天,孙梦龙,彭亮.推拿治疗骨骼肌损伤的分子生物学机制研究进展[J].湖南中医药大学学报英文版,2023,43(4):753-758.[Click to copy
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| 推拿治疗骨骼肌损伤的分子生物学机制研究进展 |
| 黄博,阮磊,王兰兰,薛惠天,孙梦龙,彭亮 |
| (湖南中医药大学针灸推拿与康复学院, 湖南 长沙 410208) |
| 摘要: |
| 骨骼肌损伤是人们生活中时常发生的一类疾患，严重者可造成肢体活动障碍。推拿治疗骨骼肌损伤类疾病有显著疗效，通过检索近5年来推拿治疗急慢性骨骼肌损伤的相关基础实验文献，对推拿治疗骨骼肌损伤的分子生物学机制研究进展进行总结、归纳，从调控肌卫星细胞、相关生长因子及炎性因子、信号通路、细胞自噬等方面进行综述，以期为临床治疗骨骼肌损伤提供有力的理论依据，并对骨骼肌损伤的研究提供新思路。 |
| 关键词: 骨骼肌损伤 推拿 修复 分子生物学机制 肌卫星细胞 细胞因子 信号通路 自噬 |
| DOI：10.3969/j.issn.1674-070X.2023.04.029 |
| Received:September 21, 2022 |
| 基金项目:国家自然科学基金项目（82174521）；湖南中医药大学研究生创新课题（2022CX109）。 |
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| Research progress on the molecular biological mechanism of tuina in treating skeletal muscle injury |
| HUANG Bo,RUAN Lei,WANG Lanlan,XUE Huitian,SUN Menglong,PENG Liang |
| (College of Acupuncture & Tuina and Rehabilitation, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Skeletal muscle injury is a common disease, and it results in limb movement disorders in severe cases. However, it is proven that tuina has significant efficacy in treating skeletal muscle injury. By searching the basic experimental literature related to tuina in treating acute or chronic skeletal muscle injury in the last 5 years, this article has summarized the research progress of the molecular biological mechanism of tuina in treating skeletal muscle injury and also has viewed the regulation of skeletal satellite cell, related growth and inflammatory factors, signaling pathways, and cellular autophagy, thus providing a strong theoretical basis for the clinical treatment of skeletal muscle injury as well as new ideas for the basic study of skeletal muscle injury. |
| Key words: skeletal muscle injury tuina repair molecular biological mechanism skeletal satellite cell cellular factors signaling pathway autophagy |
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