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刘思凡,刘平安,刘湘,刘润南,李海英,姜玲.基于不同炮制品的左金方气性迁移影响研究[J].湖南中医药大学学报英文版,2022,42(12):2037-2042.[Click to copy
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| 基于不同炮制品的左金方气性迁移影响研究 |
| 刘思凡,刘平安,刘湘,刘润南,李海英,姜玲 |
| (湖南中医药大学, 湖南 长沙 410208;湖南省儿童医院, 湖南 长沙 410007;湖南省中医药研究院 湖南 长沙 410006;湖南中医药大学, 湖南 长沙 410208;湖南省人民医院, 湖南 长沙 410005) |
| 摘要: |
| 目的 运用中药四性数学模型分析方法,探究中药不同炮制法对四气迁移的影响。方法 用数显热量仪测量大鼠服用左金方及其炮制品、前后体内代谢产物的燃烧焓,计算左金方不同炮制品在大鼠体内代谢前后的代谢物燃烧焓并分析其变化规律,判断左金方不同炮制品的药性。结果 计算得黄连-吴茱萸、黄连-制吴茱萸、姜黄连-吴茱萸、姜黄连-制吴茱萸、酒黄连-吴茱萸、酒黄连-制吴茱萸的中药四气值为:-1 852.01±46.43、-2 821.19±123.41、-1 670.82±78.99、-2 153.68±63.83、-1 367.99±121.74、-2 716.67±127.75,左金方及其炮制品根据中药四性数学模型均可判定为寒性药物,但不同炮制方法的四气值具有差异性。结论 酒制、姜制均能降低左金方的寒性,通过本文研究能正确反映炮制对中药药性的细微影响。 |
| 关键词: 气性迁移 数学模型 左金方 中药炮制 燃烧焓 生物熵 |
| DOI：10.3969/j.issn.1674-070X.2022.12.013 |
| Received:June 02, 2022 |
| 基金项目:湖南省教育厅科学研究重点项目(16A162); 湖南中医药大学校重点学科资助项目(2020YX02) |
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| Qi property migration of different processed products of Zuojin Formula |
| LIU Sifan,LIU Pingan,LIU Xiang,LIU Runnan,LI Haiying,JIANG Ling |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Children's Hospital, Changsha, Hunan 410007, China;Hunan Academy of Chinese Medicine, Changsha, Hunan 410006, China;Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial People's Hospital, Changsha, Hunan 410005, China) |
| Abstract: |
| Objective To explore the influence of different processing methods of Chinese medicine on the migration of four qi properties by the mathematical model analysis of Chinese medicine.Methods We measured the combustion enthalpies of metabolites in rats before and after administration of Zuojin Formula and its processed products by digital calorimeter, calculated the combustion enthalpies of different processed products of Zuojin Formula before and after metabolism, and analyzed the changing rules to judge the properties of different processed products of Zuojin Formula.Results The four qi values of Huanglian(Rhizoma Coptidis)-Wuzhuyu(Fructus Evodiae), Huanglian(Rhizoma Coptidis)-prepared Wuzhuyu(Fructus Evodiae), Huanglian(Rhizoma Coptidis) processed with ginger-Wuzhuyu(Fructus Evodiae), Huanglian(Rhizoma Coptidis) processed with ginger-prepared Wuzhuyu(Fructus Evodiae), Huanglian(Rhizoma Coptidis) processed with wine-Wuzhuyu(Fructus Evodiae), Huanglian(Rhizoma Coptidis)processed with wine-prepared Wuzhuyu(Fructus Evodiae) were calculated as:-1 852.01±46.43,-2 821.19±123.41,-1 670.82±78.99,-2 153.68±63.83,-1 367.99±121.74, and-2 716.67±127.75. Zuojin Formula and its processed products can be determined as cold property, and the four qi values of different processing methods are different.Conclusion Both "wine processing" and "ginger processing" can reduce the cold nature of Zuojin Formula. Our study indicated the minor effects of processing on properties of Chinese medicine. |
| Key words: qi property migration mathematical model Zuojin Formula processing of Chinese medicine combustion enthalpy biologic enthalpy |
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