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刘柘君,汤轶波,于淑俊,唐田,刘丹,刘振权.基于中医传承辅助平台探讨国医大师王琦治疗精液不液化的用药规律[J].湖南中医药大学学报英文版,2022,42(1):153-158.[Click to copy
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| 基于中医传承辅助平台探讨国医大师王琦治疗精液不液化的用药规律 |
| 刘柘君,汤轶波,于淑俊,唐田,刘丹,刘振权 |
| (北京中医药大学中医学院, 北京 100105;北京中医药大学中药学院, 北京 100105;北京中医药大学中药学院, 北京 100105;国家中医体质与治未病研究院, 北京 100029) |
| 摘要: |
| 目的 分析并总结国医大师王琦院士治疗精液不液化的组方特点和用药规律，为中医治疗精液不液化提供新的参考。方法 收集并规范王院士门诊收治精液不液化患者病例数据，通过频次分析、关联规则、聚类分析等方法对病例进行数据挖掘和可视化分析，明确核心组方并挖掘潜在新处方。结果 共纳入有效医案28份，处方51首，涉及中药77味，得出高频药物15味，性味以辛温为主，得到核心组方6组，主要有鸡内金-鱼鳔-淡豆豉、麦芽-鸡内金-山楂-淡豆豉、秦皮-车前子-麦芽-金钱草等，获得3首治疗精液不液化的新处方：鸡内金-鱼鳔-淡豆豉-麦芽-山楂、秦皮-车前子-麦芽-金钱草-山楂、菟丝子-延胡索-巴戟天-柴胡-黄芪-徐长卿。结论 王院士治疗精液不液化时强调“扶正祛邪，恢复气化功能”的用药原则，着眼于“肾阴阳失调，气化失常”的病机，临床用药以补虚药、消食药和活血化瘀药为主。 |
| 关键词: 精液不液化 王琦 国医大师 用药规律 中医传承辅助平台 阴阳失调 气化失常 |
| DOI：10.3969/j.issn.1674-070X.2022.01.028 |
| Received:August 11, 2021 |
| 基金项目:北京中医药大学纵向发展基金（2018-zxfzjj-002，81373780）。 |
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| Prescription regularity of master of traditional Chinese medicine Wang Qi in treating nonliquefaction of semen using traditional Chinese medicine inheritance assistant platform |
| LIU Zhejun,TANG Yibo,YU Shujun,TANG Tian,LIU Dan,LIU Zhenquan |
| (School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100105, China;School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100105, China;School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100105, China;National Institute of Traditional Chinese Medicine Constitution and Preventive Medicine, Beijing 100029, China) |
| Abstract: |
| Objective To summarize and analyze master of traditional Chinese medicine and academician Wang Qi's clinical prescription characteristics and prescription regularity in treating nonliquefaction of semen, so as to provide a new reference for the clinical treatment of Chinese medicine. Methods The case data of patients with nonliquefaction of semen admitted to academician Wang's outpatient clinic were collected and standardized, data mining and visual analysis of the cases were conducted through frequency analysis, association rules, cluster analysis and other methods, the core formula was clarified and potential new prescriptions was discovered. Results A total of 28 valid medical records and 51 prescriptions were included, involving 77 Chinese medicines. 15 high-frequency drugs were discovered. The nature and flavor were mainly spicy and warm. The 6 core prescriptions mainly Jineijin (Galli Gigerii Endothelium Corneum)-Yubiao (Swim Bladder)-Dandouchi (Sojae Semen Praeparatum), Maiya (Hordei Fructus Germinatus)-Jineijin (Galli Gigerii Endothelium Corneum)-Shanzha (Crataegi Fructus)-Dandouchi (Sojae Semen Praeparatum), Qinpi (Fraxini Cortex)- Cheqianzi (Plantaginis Semen)-Maiya (Hordei Fructus Germinatus)-Jinqiancao (Lysimachiae Herba), etc. 3 new prescriptions for the treatment of nonliquefaction of semen were obtained, namely Jineijin (Galli Gigerii Endothelium Corneum)-Yubiao (Swim Bladder)-Dandouchi (Sojae Semen Praeparatum)-Maiya (Hordei Fructus Germinatus)-Shanzha (Crataegi Fructus), Qinpi (Fraxini Cortex)-Cheqianzi (Plantaginis Semen)-Maiya (Hordei Fructus Germinatus)-Jinqiancao (Lysimachiae Herba)-Shanzha (Crataegi Fructus), Tusizi (Cuscutae Semen)-Yanhusuo (Corydalis Rhizoma)-Bajitian (Morindae Officinalis Radix)-Chaihu (Bupleuri Radix)-Huangqi (Astragali Radix)-Xuchangqing (Cynanchi Paniculati Radix Et Rhizoma). Conclusion Academician Wang emphasizes the medication principle of "strengthening the vital to eliminate pathogenic factor and restoring the function of Qi" when treating nonliquefaction of semen, focusing on the pathogenesis of "the disorder of kidney Yin and Yang, and the disorder of movement and change of Qi". The clinical prescription is mainly based on tonic medicine, digestion drugs and blood circulation drugs. |
| Key words: nonliquefaction of semen Wang Qi master of traditional Chinese medicine prescription regularity traditional Chinese medicine inheritance assistant platform disorder of Yin and Yang disorder of movement and change of Qi |
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