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刘剑,王婷,黄河,陈涛,彭洪亮,邓光程.肾石通颗粒联合体外冲击波碎石治疗输尿管结石湿热证的疗效观察[J].湖南中医药大学学报英文版,2021,41(8):1280-1284.[Click to copy
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| 肾石通颗粒联合体外冲击波碎石治疗输尿管结石湿热证的疗效观察 |
| 刘剑,王婷,黄河,陈涛,彭洪亮,邓光程 |
| (湖南中医药大学第一附属医院, 湖南 长沙 410007;长沙市第四医院, 湖南 长沙 410006) |
| 摘要: |
| 目的 观察肾石通颗粒（无糖型）联合体外冲击波碎石治疗输尿管结石湿热证的临床疗效。方法 将长沙市第四医院收治的192例输尿管结石湿热证患者按数字表法随机分为两组，每组96例。对照组行体外冲击波碎石治疗，观察组在体外冲击波碎石治疗的基础上联合应用肾石通颗粒（无糖型），疗程为14 d。观察并比较两组治疗后的总有效率、排石率、肾绞痛发生率、下尿路刺激征及肉眼血尿等并发症的发生率；并比较两组治疗前与治疗后的视觉模拟评分、血白细胞、C反应蛋白、血肌酐水平。结果 观察组总有效率、排石率明显高于对照组（P<0.05）；观察组肾绞痛发生率、下尿路刺激征发生率、肉眼血尿发生率明显低于对照组（P<0.05）；治疗后，两组视觉模拟评分、血白细胞、C反应蛋白、血肌酐水平均较治疗前下降，且观察组较对照组下降更为明显（P<0.05）。结论 肾石通颗粒（无糖型）能安全且有效治疗体外冲击波碎石后输尿管结石湿热证。 |
| 关键词: 肾石通颗粒 体外冲击波碎石 输尿管结石 视觉模拟评分 血白细胞 C反应蛋白 血肌酐 |
| DOI：10.3969/j.issn.1674-070X.2021.08.026 |
| Received:May 15, 2021 |
| 基金项目:湖南省西学中骨干人才培养项目；湖南省卫生健康委一般资助项目（202104072040）。 |
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| Efficacy Observation on Shenshitong Granule Combined with Extracorporeal Shock Wave Lithotripsy in the Treatment of Ureteral Calculus Damp-heat Syndrome |
| LIU Jian,WANG Ting,HUANG He,CHEN Tao,PENG Hongliang,DENG Guangcheng |
| (The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;The Fourth Hospital of Changsha, Changsha, Hunan 410006, China) |
| Abstract: |
| Objective To observe the clinical effect of Shenshitong Granule (sugar-free type) combined with extracorporeal shock wave lithotripsy in the treatment of ureteral calculus damp-heat syndrome. Methods 192 patients with ureteral calculus damp-heat syndrome admitted to The Fourth Hospital of Changsha were randomly divided into two groups according to the number table, 96 cases in each group. The control group was treated with extracorporeal shock wave lithotripsy, the observation group was treated with extracorporeal shock wave lithotripsy combined with Shenshitong Granule for 14 days. The total effective rate, stone-removal effect, renal colic, lower urinary tract irritation symptom, macroscopic hematuria were observed and compared of the two groups after treatment; visual analog scale, white blood cell, C-reactive protein and serum creatinine value were compared before and 2 weeks after treatment. Results The total effective rate and stone-removal effect of observation group were significantly higher than those in the control group (P<0.05). The incidence of renal colic, lower urinary tract irritation symptom, macroscopic hematuria of the observation group were significantly lower than those in the control group (P<0.05). After treatment, visual analog score, leukocyte, C-reactive protein and serum creatinine levels in both groups decreased compared with those before treatment, and the observation group decreased more significantly than the control group (P<0.05). Conclusion Shenshitong Granule (sugar-free type) can safely and effectively treat the ureteral calculi damp-heat syndrome after extracorporeal shock wave lithotripsy. |
| Key words: Shenshitong Granule extracorporeal shock wave lithotripsy ureteral calculus visual analog scale white blood cell C-reactive protein creatinine |
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