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熊家青,徐基平,李逵,吴泳蓉,黄晓蒂,田莎,吴若霞,田雪飞.基于玄府理论探讨芳香开通法在肿瘤化疗后粒细胞减少治疗中的运用[J].湖南中医药大学学报英文版,2020,40(10):1257-1260.[Click to copy
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| 基于玄府理论探讨芳香开通法在肿瘤化疗后粒细胞减少治疗中的运用 |
| 熊家青,徐基平,李逵,吴泳蓉,黄晓蒂,田莎,吴若霞,田雪飞 |
| (湖南中医药大学附属衡阳医院, 湖南 衡阳 421001;湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学中西医结合学院, 湖南 长沙 410208) |
| 摘要: |
| 玄府是气机升降出入的门户，玄府通则营卫和，玄府闭则百病生。化疗后玄府郁闭是阻碍粒细胞进入外周血，造成粒细胞减少的关键因素，也是影响益气养血法治疗化疗后粒细胞减少疗效的重要原因。芳香开窍药物具有芳香辛散，通达脉络功效。从“通”的角度探讨芳香开窍药开通玄府的作用，并提出“开通玄府促骨髓粒细胞进入外周血”的假说，为今后开展化疗后粒细胞减少的中医药研究工作提供思路。 |
| 关键词: 肿瘤 化疗 粒细胞减少 玄府理论 芳香开通 |
| DOI：10.3969/j.issn.1674-070X.2020.10.016 |
| Received:July 14, 2020 |
| 基金项目:国家自然科学基金项目（81603603，81473617）；湖南省教育厅开放平台基金项目（16K066）；湖南省科技计划项目（2017SK50310）；湖南中医药大学中西医结合一流学科开放基金（2018ZXYJH28，2018ZXYJH03，2018ZXYJH04）；湖南省研究科研创新项（CX20190541）；湖南省教育厅优秀青年项目（19B423）；湖南省自然科学基金青年基金项目（2020JJ5440）。 |
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| Exploring the Application of Aromatic Opening Method in Treating Granulocyte Reduction After Tumor Chemotherapy from Xuanfu Theory |
| XIONG Jiaqing,XU Jiping,LI Kui,WU Yongrong,HUANG Xiaodi,TIAN Sha,WU Ruoxia,TIAN Xuefei |
| (Hengyang Hospital Affiliated to Hunan University of Chinese Medicine, Hengyang, Hunan 421001, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;School of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Xuanfu is the gateway for the ascending and descending of Qi movement. Smooth Xuanfu leads to harmony between nutrient Qi and defensive Qi, while blocked Xuanfu causes diseases. Xuanfu depression after chemotherapy is a key factor that prevents granulocytes from entering the peripheral blood and causing neutropenia. It is also an important reason for influencing the effect of Yiqi Yangxue therapy on neutropenia after chemotherapy. The herbs of resuscitation with aromatics have effects of aroma and pungent, and reaching meridians and collaterals. This paper discussed the role of herbs of resuscitation with aromatics in the opening of Xuanfu from the perspective of "smooth", and proposed the hypothesis of "opening Xuanfu to promote the entry of bone marrow granulocytes into peripheral blood", so as to provide ideas for traditional Chinese medicine research work on neutropenia after chemotherapy. |
| Key words: tumor chemotherapy neutropenia Xuanfu theory aroma opening |
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