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黄费炳,吴嘉,盛文兵,彭彩云,王炜,张在其,李斌,陈胜璜.三叶委陵菜的化学成分和药理作用研究进展[J].湖南中医药大学学报英文版,2020,40(8):1039-1044.[Click to copy
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| 三叶委陵菜的化学成分和药理作用研究进展 |
| 黄费炳,吴嘉,盛文兵,彭彩云,王炜,张在其,李斌,陈胜璜 |
| (湖南中医药大学药学院中药民族药物创新发展国际实验室, 中巴医药民族医药研究国际合作基地, 湖南 长沙 410208;湖南医药学院, 侗医药研究湖南省重点实验室, 湖南 怀化 418000) |
| 摘要: |
| 三叶委陵菜作为一种重要民间药物，在我国广泛分布于湖北、湖南、河北等地区。三叶委陵菜的主要成分为黄酮、鞣质、三萜、甾体等，具有肝保护、抗炎镇痛、抑菌、抗病毒、抗氧化、调节免疫等药理作用。本篇综述了目前三叶委陵菜的化学成分及药理作用研究进展，以期为三叶委陵菜的进一步药效药理研究与开发提供基础。 |
| 关键词: 三叶委陵菜 黄酮 萜类 抗炎 镇痛 抗病毒 |
| DOI：10.3969/j.issn.1674-070X.2020.08.024 |
| Received:May 21, 2020 |
| 基金项目:侗医药研究湖南省重点实验室（2015TP1020-02）；侗医药研究湖南省重点实验室平台建设（2017CT5025）；中医诊断学国家重点学科开放基金项目(2015ZYZD06)。 |
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| Research Progress on Chemical Constituents and Pharmacological Activities of Potentilla freyniana Bornm |
| HUANG Feibing,WU Jia,SHENG Wenbing,PENG Caiyun,WANG Wei,ZHANG Zaiqi,LI Bin,CHEN Shenghuang |
| (International Laboratory on TCM and Ethnomedicine Innovation&Development, Sino-Pakistan TCM&Ethnomedicine International Cooperation Base, Changsha, Hunan 410208 China;Hunan University of Medicine, Hunan Provincial Key Laboratory of Dong Medicine, Huaihua, Hunan 418000, China) |
| Abstract: |
| Potentilla freyniana Bornmis is an important folk medicine, and widely distributed in Hubei, Hunan, and Hebei province of China. The main chemical components of Potentilla freyniana Bornmis are flavonoids, tannins, triterpenes and steroids, which have multiple pharmacological activities such as liver protection, anti-inflammatory and analgesic, antibacterial, antiviral, antioxidant, and immune regulation. This paper reviewed the current research progress of chemical constituents and pharmacological activities of Potentilla freyniana Bornm, so as to provide foundation for further pharmacodynamic research and development of Potentilla freyniana Bornm. |
| Key words: Potentilla freyniana Bornm flavonoids terpenoids anti-inflammatory analgesic antiviral |
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