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施利,裴异.中医药治疗初治肺结核临床用药规律研究[J].湖南中医药大学学报英文版,2020,40(8):1018-1021.[Click to copy
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| 中医药治疗初治肺结核临床用药规律研究 |
| 施利,裴异 |
| (南华大学附属长沙中心医院, 湖南 长沙 410008) |
| 摘要: |
| 目的 分析中医药治疗初治肺结核的临床用药规律。方法 纳入中医药治疗初治肺结核文献，分析方剂的药物组成、功效分类、治法等情况，进而探讨其用药规律。结果 共纳入35篇文献，收集中药方剂35首，涉及药物123味，药物总频次390次，其中药物使用频数最高的前5味依次为百部、沙参、麦冬、甘草、黄芪；药物功效使用频数最高的前3类为补益、清热、化痰止咳平喘药；方药治法使用频数最高的前3种为滋阴润肺、益气补虚、解毒杀虫法；聚类分析提炼出5组核心药物群，分别为：百部，沙参与麦冬，黄芪、生地黄、甘草与白及，川贝、黄芩与百合，当归、熟地黄、地骨皮、党参与鳖甲。结论 中医治疗初治肺结核的基本思路是扶正与杀虫并行，益气养阴、补虚培元以扶正，抗痨杀虫以除因，标本兼顾整体治疗，可取得良好的效果。 |
| 关键词: 初治肺结核 中医药疗法 用药规律 |
| DOI：10.3969/j.issn.1674-070X.2020.08.020 |
| Received:February 24, 2020 |
| 基金项目:湖南省中医药管理局项目（201890）。 |
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| Study on Clinical Medication Rules of Chinese Materia Medica in the Treatment of Primary Tuberculosis |
| SHI Li,PEI Yi |
| (Changsha Central Hospital Affiliated to University of South China, Changsha, Hunan 410008, China) |
| Abstract: |
| Objective To analyze the medication rules of Chinese materia medica in the treatment of primary tuberculosis. Methods The literature on Chinese materia medica in the primary tuberculosis was included to analyze the drug composition, functional classification and treatment principle of the prescription, and then to explore the medication rules. Results A total of 35 literatures were included, and 35 Chinese materia medica prescriptions were collected, involving 123 herbs, with a total frequency of 390 times. The top 5 most frequently used herbs were Radix Stemonae, Radix Glehniae, Radix Ophiopogonis, Radix Glycyrrhizae and Radix Astragali seu Hedysari. The top 3 most frequently used herbs in efficacy were tonic, heat-clearing, relieving phlegm and cough and anti-asthmatic. The top 3 most common methods of prescription treatment were nourishing Yin and moistening lung, benefiting Qi and supplementing deficiency, and detoxicating and killing insects. 5 groups of core herbs were extracted by cluster analysis, which were as follows:Radix Stemonae; Radix Glehniae and Radix Ophiopogonis; Radix Astragali seu Hedysari, Radix Rehmanniae Recens, Radix Glycyrrhizae and Rhizoma Bletillae; Bulbus Fritillariae Cirrhosae, Radix Scutellariae and Bulbus Lilii; Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Cortex Lycii, Radix Codonopsis and Carapax Trionycis. Conclusion The basic idea of traditional Chinese medicine for the treatment of tuberculosis is to both strengthen healthy Qi and kill insects. Benefiting Qi and nourishing Yin, tonifying deficiency and cultivating primordial spirit are performed to strengthen healthy Qi. Anti-tuberculosis and killing insects are performed to remove root causes. Treatment of symptoms and root causes and considering the overall efficacy can achieve the ideal effect. |
| Key words: primary tuberculosis traditional Chinese medicine therapy medication rule |
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