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张晨阳,杨少锋,聂颖,李兆勇,吴肖男,李玲.杨少锋教授治疗腰椎间盘突出症用药规律研究[J].湖南中医药大学学报英文版,2020,40(6):722-726.[Click to copy
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| 杨少锋教授治疗腰椎间盘突出症用药规律研究 |
| 张晨阳,杨少锋,聂颖,李兆勇,吴肖男,李玲 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 目的 利用数据挖掘分析杨少锋教授治疗腰椎间盘突出症用药规律。方法 收集整理杨少锋教授治疗腰椎间盘突出症患者307例，对符合纳入标准病例中的中药处方进行统计，采用SPSS 21和SPSS Modeler 14对中药的频数、频率、归经、聚类和关联规则进行分析。结果 （1）选取符合统计要求的中药67味，累计使用4 689次，其中甘草、桂枝、大枣、白芍等21味中药为高频次用药。（2）补虚药、解表药、活血化瘀药为常用中药类别。（3）高频中药归经以脾经、肺经、肾经为主。（4）聚类分析结果第一类：桂枝、大枣、生姜、甘草、白芍、鸡血藤、人参、威灵仙、细辛，此基本方为桂枝汤新加汤。（5）常用药对为柴胡与枳实、威灵仙与枳实、杜仲与牛膝、生姜与大枣等。结论 杨少锋教授善用六经辨证诊治腰椎间盘突出症，在经方的基础上加入补虚药、活血化瘀药，临床疗效好，为中医药诊疗腰椎间盘突出症提供思路及参考。 |
| 关键词: 腰椎间盘突出症 六经辨证 补虚 解表 活血化瘀 杨少锋 |
| DOI：10.3969/j.issn.1674-070X.2020.06.016 |
| Received:December 06, 2019 |
| 基金项目:湖南省自然科学基金项目(2017JJ2208，2019JJ80071）。 |
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| Research on the Medication Rule of Professor YANG Shaofeng in the Treatment of Lumbar Disc Herniations |
| ZHANG Chenyang,YANG Shaofeng,NIE Ying,LI Zhaoyong,WU Xiaonan,LI Ling |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Objective To explore the law of medication of Professor YANG Shaofeng in the treatment of lumbar disc herniations based on data mining. Methods A total of 307 cases of patients with lumbar disc herniations treated by Professor YANG Shaofeng were collected and sorted out, and the prescriptions of Chinese materia medica in accordance with the inclusion criteria were sent for statistics. The number, frequency, meridian tropism, clustering and association rules of Chinese materia medica were analyzed by SPSS 21 and SPSS modeler 14. Results (1) 67 types of Chinese materia medica that meet the statistical requirements were selected, with a total of 4689 times of usage. Among them, 21 types of Chinese materia medica such as Radix Glycyrrhizae, Ramulus Cinnamomi, Fructus Jujubae and Radix Paeoniae Alba were used as high-frequency drugs. (2) Tonifying deficiency drugs, relieving superficies drugs and activating blood and resolving stasis drugs were commonly used types. (3) The meridian tropism of Chinese materia medica with high-frequency was mainly spleen meridian, lung meridian and kidney meridian. (4) Cluster analysis showed that the first category was Ramulus Cinnamomi, Fructus Jujubae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, Radix Paeoniae Alba, Caulis Spatholobi, Radix Ginseng, Radix Clematidis and Herba Asari. This basic prescription was newly added Guizhi Decoction. (5) The common drug pairs were Radix Bupleuri and Fructus Aurantii Immaturus, Radix Clematidis and Fructus Aurantii Immaturus, Cortex Eucommiae and Radix Achyranthis Bidentatae, Rhizoma Zingiberis Recens and Fructus Jujubae. Conclusion Professor YANG Shaofeng is good at the diagnosis and treatment of lumbar disc herniations based on syndrome differentiation of six meridians. On the basis of classical prescriptions, we add the medicine of tonifying deficiency, activating blood circulation and removing blood stasis, with good clinical efficacy, which will bring forth new ideas and references for the diagnosis and treatment of lumbago by traditional Chinese medicine |
| Key words: lumbar disc herniation syndrome differentiation of six meridians tonifying deficiency relieving superficies activating blood and resolving stasis YANG Shaofeng |
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