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张萌,孙芮,张楠,刘果,赵岩松.基于中医传承辅助平台探讨中药改善子宫内膜容受性的用药规律[J].湖南中医药大学学报英文版,2020,40(4):434-439.[Click to copy
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| 基于中医传承辅助平台探讨中药改善子宫内膜容受性的用药规律 |
| 张萌,孙芮,张楠,刘果,赵岩松 |
| (北京中医药大学, 北京 100029) |
| 摘要: |
| 目的 应用中医传承辅助平台软件，分析和总结中医药改善子宫内膜容受性的组方用药规律。方法 收集中国知网、维普、万方、中国生物医学文献数据库以及PubMed数据库中中医药改善子宫内膜容受性的近十年文献，筛选出符合标准的方剂并建立数据库，应用中医传承辅助系统（V2.5）软件中集成的数据挖掘方法，分析方剂中中药用药规律。结果 共筛选出符合标准的方剂65条，涉及中药110味，计算得出使用频次较高的药物：菟丝子、当归、熟地黄、川芎、香附、白芍和丹参等；得到改善子宫内膜容受性的常用药物组合，以菟丝子、当归、熟地黄和白芍两两组合最多；进一步聚类，得到3个新处方。结论 通过中医传承辅助平台对改善子宫内膜容受性的方剂数据进行分析，认为中医药治疗低子宫内膜容受性注重补益肝肾、调理气血，所得新方组合仍需通过临床辨证运用以验证其效。 |
| 关键词: 中医传承辅助平台 子宫内膜容受性 组方用药规律 |
| DOI：10.3969/j.issn.1674-070X.2020.04.010 |
| Received:November 17, 2019 |
| 基金项目:国家自然科学基金面上项目（81873214）；北京中医药薪火传承“3+3”工程项目（2016-SZ-C-64）；北京中医药大学中青年教师培育项目（2016-JYB-JSPY-004）。 |
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| Study on the Law of Chinese Materia Medica in Improving Endometrial Receptivity Based on Traditional Chinese Medicine Inheritance Assistant Platform |
| ZHANG Meng,SUN Rui,ZHANG Nan,LIU Guo,ZHAO Yansong |
| (Beijing University of Chinese Medicine, Beijing 100029, China) |
| Abstract: |
| Objective To analyze and summarize the rules of Chinese materia medica in improving endometrial receptivity by using traditional Chinese medicine (TCM) inheritance assistant platform software. Methods The literatures about the improvement of endometrial receptivity by Chinese materia medica published in the past 10 years were collected from the databases of CNKI, VIP, Wanfang, Chinese biomedical literature and PubMed. The prescriptions that meet the standards were screened to establish database. The data mining method integrated in the TCM inheritance assistant platform software v2.5 to analyze the rules of Chinese materia medica used in the prescriptions. Results A total of 65 prescriptions were screened out, involving 110 kinds of Chinese materia medica. The frequency of drug use in the prescriptions was calculated. The drugs with higher frequency were Semen Cuscutae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Ligustici Chuanxiong, Rhizoma Cyperi, Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, etc.; The commonly used drug pairs to improve endometrial receptivity were obtained, with drug pairs of Semen Cuscutae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata and Radix Paeoniae Alba as the most; For further cluster analysis, 3 new prescriptions were obtained. Conclusion Based on the analysis of the data of recipe for improving endometrial receptivity through TCM inheritance assistant platform, it is believed that TCM treatment of low endometrial receptivity focuses on tonifying the liver and kidney, regulating Qi and blood, and the combination of new recipes still needs to be verified by clinical syndrome differentiation and application. |
| Key words: traditional Chinese medicine inheritance assistant platform endometrial receptivity regularity of medication prescription |
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