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辜洁敏,陈超,陈秋铭,纪淑萍.基于数据挖掘分析国医大师治疗消渴病用药规律[J].湖南中医药大学学报英文版,2019,39(12):1483-1487.[Click to copy
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| 基于数据挖掘分析国医大师治疗消渴病用药规律 |
| 辜洁敏,陈超,陈秋铭,纪淑萍 |
| (广州中医药大学附属汕头中医院, 广东 汕头 515031) |
| 摘要: |
| 目的 基于数据挖掘分析国医大师治疗消渴病验案用药规律。方法 收集国医大师治疗消渴病验案中符合纳入标准的方剂39首，涉及中药141种。利用Excel2007软件建立方药数据库，并采用频数分析、聚类分析、关联分析等方法进行统计分析。结果 频数分析显示国医大师治疗消渴病用药以补益药、清热药、利水渗湿药为主，辅以利水渗湿、收涩、活血化瘀等药，性味以甘、寒为主；药物多归肝脾肺经。通过聚类分析归纳出六味地黄丸和玉液汤为主的核心药物群，具体药物包括：黄芪、山药、知母、牡丹皮、泽泻、熟地黄、山茱萸、丹参、五味子、葛根、天花粉等。结论 国医大师治疗消渴病的用药方面具有补虚为主、祛邪实为辅、注重行肝药的使用、注重阴阳平衡、动静结合等鲜明的特点。 |
| 关键词: 消渴病 医案 国医大师 用药规律 数据挖掘 |
| DOI：10.3969/j.issn.1674-070X.2019.12.014 |
| Received:June 18, 2019 |
| 基金项目:广东省中医药局科研项目（20193012）。 |
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| Data Mining-based Analysis of Drug Use Rules of Traditional Chinese Medicine Masters in the Treatment of Diabetes |
| GU Jiemin,CHEN Chao,CHEN Qiuming,JI Shuping |
| (Shantou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Shantou, Guangdong 515031, China) |
| Abstract: |
| Objective Based on data mining, to analyze the rule of medication used by traditional Chinese medicine (TCM) masters in the treatment of diabetes mellitus. Methods A total of 39 prescriptions, involving 141 kinds of Chinese herbal medicines, which met the inclusion criteria were collected.from the medical records of TCM masters in the treatment of diabetes mellitus. The database of prescriptions and medicines was established by Excel 2007 software. Frequency analysis, clustering analysis and correlation analysis were used for statistical analysis. Results Frequency analysis showed that the main drugs for TCM masters in the treatment of diabetes were tonic drugs, heat-clearing drugs and water-diffusing and dampness-diffusing drugs, supplemented by water-diffusing and dampness-diffusing drugs, astringent drugs, blood-activating and blood-stasis-removing drugs. The main flavor was sweet and cold, and most of the drugs belonged to the liver, spleen and lung meridians. Through cluster analysis, the core drug groups of Liuwei Dihuang Pills and Yuye Decoction were concluded, including Radix Astragaliseu Hedysari, Rhizoma Dioscoreae, Cortex Moutan Radicis, Rhizoma Alismatis, Radix Rehmanniae Preparata, Fructus Corni, Radix Salviae Miltiorrhizae, Fructus Schisandrae Chinensis, Radix Puerariae, Radix Trichosanthis. Conclusion In the treatment of diabetes, TCM masters have the distinct characteristics of mainly tonifying deficiency, supplemented by dispelling pathogenic factors and excess, paying attention to the use of hepatic drugs, balancing Yin and Yang, and combining motility with rest. |
| Key words: diabetes mellitus law of medication traditional Chinese medicine masters medical records data mining |
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