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谭朝坚,兰伟,兰红勤,张志,廖舟,邓文剑,徐梦鸽.针刺调理糖耐量异常兼见痰湿体质人群的临床研究[J].湖南中医药大学学报英文版,2019,39(11):1377-1381.[Click to copy
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| 针刺调理糖耐量异常兼见痰湿体质人群的临床研究 |
| 谭朝坚,兰伟,兰红勤,张志,廖舟,邓文剑,徐梦鸽 |
| (湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学, 湖南 长沙 410208) |
| 摘要: |
| 目的 通过辨识糖耐量异常人群的中医体质，并依据体质选取穴位，探索临床上针灸干预糖耐量异常兼见痰湿体质的优化治疗方案。方法 将66例糖耐量异常兼见痰湿体质的受试者，随机分为治疗组（针刺+生活方式干预）和对照组（生活方式干预）各33例，观察3个疗程后比较两组的空腹血糖（fasting plasma glucose，FPG）、餐后2 h血糖（2-hour postprandial blood glucose，2hPG）、糖化血红蛋白（glycohemoglobin，HbA1c）、空腹胰岛素（fasting insulin，FINS）、餐后2 h胰岛素（2 hours fasting insulin，2hINS）以及中医痰湿体质积分等指标的改变，客观评价针刺干预糖耐量异常以及调理痰湿体质的治疗效果。结果 （1）两组治疗后FPG、2hPG、HbA1c、FINS、2hINS、痰湿体质积分等指标均较治疗前有明显改善（P<0.05），且除FPG两组差异不明显外（P>0.05），其余指标治疗组的干预效果明显优于对照组（P<0.05）；（2）治疗后治疗组痰湿体质改善程度与对照组比较，差异具有显著性意义（P<0.05）；（3）两组干预糖耐量异常的疗效和生活方式干预依从性比较，差异均无统计学意义（P>0.05）。结论 根据体质不同选取相应穴位，运用针刺手段干预痰湿体质兼见糖耐量异常人群的疗效具有一定的优势，可以在临床进一步推广运用。 |
| 关键词: 糖耐量异常 痰湿体质 针刺 痰湿体质积分 FPG FINS 2hPG HbA1c |
| DOI：10.3969/j.issn.1674-070X.2019.11.019 |
| Received:April 10, 2019 |
| 基金项目:湖南中医药大学校级科研课题基金（ZYYDX201732）。 |
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| Clinical Study on Acupuncture Treatment of People with Phlegm-dampness Constitution and Impaired Glucose Tolerance |
| TAN Chaojian,LAN Wei,LAN Hongqin,ZHANG Zhi,LIAO Zhou,DENG Wenjian,XU Mengge |
| (The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective By identifying the traditional Chinese medicine(TCM) constitution of people with impaired glucose tolerance and selecting acupoints according to their constitution to explore the optimal therapeutic scheme of acupuncture intervention in people with phlegm-dampness constitution and impaired glucose tolerance. Methods A total of 66 subjects with impaired glucose tolerance and phlegm-dampness constitution were randomly divided into a treatment group (acupuncture + lifestyle intervention) and a control group (lifestyle intervention), with 33 cases in each group. After 3 courses of treatment, the 2 groups were compared. The changes of 6 indicators:fasting plasma glucose (FPG), 2-hour postprandial plasma glucose (2hPG), glycohemoglobin (HbA1c), fasting insulin (FINS), 2-hour postprandial insulin (2hINS) and TCM phlegm-dampness scores were observed to objectively evaluate the therapeutic effect of acupuncture intervention on impaired glucose tolerance and phlegm-dampness. Results (1) After treatment, FPG, 2hPG, HbA1c, FINS, 2hINS, and TCM phlegm-dampness scores showed apparent improvement in both groups (P<0.05). Those changes of indicators in the treatment group were improved more significantly than the control group (P<0.05), except the FPG differences were not as significant (P>0.05). (2) After treatment, the improvement of phlegm-dampness constitution in the treatment group had significant difference when compared with that of the control group (P<0.05). (3) The efficacy differences of impaired glucose tolerance treatment with lifestyle intervention in both groups had no statistical significance (P>0.05). Conclusion It is inferred that acupuncture on acupoints selected by different constitution has certain advantages in treating people with phlegm-dampness and impaired glucose tolerance and can be further promoted and applied in the clinic. |
| Key words: impaired glucose tolerance phlegm-dampness constitution acupuncture clinical research FPG FINS 2hPG HbA1c |
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