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李耀伟,朱晨晨,王志琪,彭兰,张序晴,曾嵘,任卫琼,邓凯文.附子温阳作用与解毒方法关联初探[J].湖南中医药大学学报英文版,2019,39(6):781-785.[Click to copy
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| 附子温阳作用与解毒方法关联初探 |
| 李耀伟,朱晨晨,王志琪,彭兰,张序晴,曾嵘,任卫琼,邓凯文 |
| (湖南中医药大学研究生院, 湖南 长沙 410208;湖南中医药大学中西结合学院, 湖南 长沙 410208;湖南中医药大学药学院, 湖南 长沙 410208;湖南省中药饮片标准化及功能工程技术中心, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 附子为温阳之要药，在中医临床中用于治疗不同程度的虚寒证疾病。历代医书均记载附子有毒或有大毒，临床使用附子时，多通过炮制和配伍以解毒。为阐明中医临床运用附子在确保其安全的同时，如何实现疗效最大化，本文首先对含有附子的经方进行了文献总结与归纳，在此基础上探讨附子在发挥不同程度的温阳作用时，与解毒方法之间的关联，以总结其规律。 |
| 关键词: 附子 温阳 减毒增效 毒效关系 |
| DOI：10.3969/j.issn.1674-070X.2019.06.024 |
| Received:August 22, 2018 |
| 基金项目:国家自然科学基金项目（81503492），湖南省自然科学基金项目（2015JJ6079），湖南省教育厅教改项目（湘教通[2016]400-321），湖南省大学生研究性学习和创新性实验计划项目（湘教通[2018]255-414），湖南中医药大学教改项目（2018-JG021），国家中医药管理局中药标准化建设项目（ZYBZH-Y-HUN-24）。 |
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| Preliminary Study on the Relationship Between the Function of Warming Yang and Detoxification Methods of Radix Aconiti Lateralis Praeparata |
| LI Yaowei,ZHU Chenchen,WANG Zhiqi,PENG Lan,ZHANG Xuqing,ZENG Rong,REN Weiqiong,DENG Kaiwen |
| (Graduate School of Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;School of Chinese and Western Integration, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;College of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Center of Traditional Chinese Medicine Pieces Standardization and Functional Engineering Technology, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Radix Aconiti Lateralis Praeparata is an essential medicine for warming Yang, and is used in the clinical practice of traditional Chinese medicine (TCM) to treat different degrees of diseases with deficiency-cold syndrome. Medical books of all dynasties recorded that Radix Aconiti Lateralis Praeparata was toxic or hypertoxic. When Radix Aconiti Lateralis Praeparata was used clinically, it was usually detoxified through processing and combination. In order to elucidate how to maximize the efficacy of Radix Aconiti Lateralis Praeparata and ensure its safety in TCM clinical practice, this paper summarized and concluded the literature of the prescriptions containing Radix Aconiti Lateralis Praeparata, and thereby discusses the relationship between different-degree warming Yang function of Radix Aconiti Lateralis Praeparata and detoxification methods to summarize its rules. |
| Key words: Radix Aconiti Lateralis Praeparata warming Yang toxicity reducing and efficacy enhancing toxicity-efficacy relationship |
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