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欧晨,彭晓芳,李银鑫,秦惠钰,陈向东,彭清华.中医药治疗糖尿病视网膜病变光凝术后疗效的Meta分析[J].湖南中医药大学学报英文版,2018,38(12):1407-1411.[Click to copy
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| 中医药治疗糖尿病视网膜病变光凝术后疗效的Meta分析 |
| 欧晨,彭晓芳,李银鑫,秦惠钰,陈向东,彭清华 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 目的 运用Meta分析方法系统评价中医药治疗糖尿病视网膜病变（diabetic retinopathy，DR）光凝术后疗效。方法 检索Pubmed、Medline、Cochrane Library、维普期刊数据库、中国知网和万方数据库中的中医治疗糖尿病视网膜病变光凝术后的随机对照研究，由两名评价者独立提取资料并进行方法学质量评估，数据分析采用Rev Man5.3软件进行统计分析。结果 共纳入10个随机对照研究，包括883例患者。中医药治疗DR光凝术后总疗效优于对照组[OR=3.77，95% CI （2.59，5.48），P<0.000 01]；中医药治疗DR光凝术后消退黄斑水肿的疗效优于对照组[OR=4.05，95% CI （1.75，9.37），P=0.001]；中医药治疗DR光凝术后减少眼底出血的疗效优于对照组[OR=3.58，95% CI （1.72，7.42），P=0.000 6]。结论 中医药治疗有利于患者消退黄斑水肿和减少眼底出血，在治疗DR光凝术后总体疗效上更有优势。 |
| 关键词: 糖尿病视网膜病变 光凝术 中医药 Meta分析 |
| DOI：10.3969/j.issn.1674-070X.2018.12.012 |
| Received:March 21, 2018 |
| 基金项目:湖南省自然科学基金项目（2015JJ2109）；湖南省中医药科研计划项目（201463）；湖南省中医药管理局科研课题（2017141）；国家中医药管理局中医眼科学重点学科建设项目；湖南省中医五官科重点学科建设项目；中医药防治眼耳鼻咽喉疾病湖南省重点实验室资助项目；中央财政支持地方高校资助项目。 |
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| A Meta-analysis of the Therapeutic Efficacy of Traditional Chinese Medicine in Treatment of Diabetic Retinopathy After Photocoagulation |
| OU Chen,PENG Xiaofang,LI Yinxin,QIN Huiyu,CHEN Xiangdong,PENG Qinghua |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Objective To systematically evaluate the therapeutic efficacy of traditional Chinese medicine (TCM) in the treatment of diabetic retinopathy (DR) after photocoagulation using meta-analysis.Methods Randomized controlled trials of TCM in the treatment of DR after photocoagulation were retrieved from PubMed, Medline, the Cochrane Library, VIP, CNKI, and Wanfang Data. Two reviewers independently extracted data and performed methodological quality assessment. Data analysis was performed using RevMan 5.3.Results A total of ten randomized controlled trials involving 883 patients were included. In the TCM treatment of DR after photocoagulation, the overall therapeutic efficacy was significantly better in the treatment group than in the control group (odds ratio[OR]=3.77, 95% confidence interval[CI] (2.59, 5.48), P<0.000 01); the therapeutic efficacy of resolving macular edema after photocoagulation was significantly better in the treatment group than in the control group[OR=4.05, 95% CI (1.75, 9.37), P=0.001]; the therapeutic efficacy of reducing fundus hemorrhage after photocoagulation was significantly better in the treatment group than in the control group[OR=3.58, 95% CI (1.72, 7.42), P=0.000 6].Conclusion TCM treatment is beneficial for patients to resolve macular edema and reduce fundus hemorrhage, and it is more advantageous in terms of its overall therapeutic efficacy in the treatment of DR after photocoagulation. |
| Key words: diabetic retinopathy photocoagulation traditional Chinese medicine meta-analysis |
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