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周蕾,王梦楠,朱霄,程慧敏,王语馨,杜帆,郭冷秋.刺五加对中枢神经系统的活性成分、药理作用及临床应用[J].湖南中医药大学学报英文版,2018,38(8):961-964.[Click to copy
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| 刺五加对中枢神经系统的活性成分、药理作用及临床应用 |
| 周蕾,王梦楠,朱霄,程慧敏,王语馨,杜帆,郭冷秋 |
| (苏州卫生职业技术学院药学院, 江苏 苏州 215000) |
| 摘要: |
| 本文通过梳理近十年来国内外关于刺五加在中枢神经系统方面的研究文献，阐述刺五加对中枢神经系统作用的活性成分主要为皂苷类和黄酮类成分；刺五加在中枢神经系统方面具有改善睡眠、增强学习记忆、抗抑郁、抗帕金森病等作用和临床应用，但关于刺五加对多种神经系统疾病的作用机制尚不十分清楚，以期为刺五加治疗中枢神经系统方面的疾病提供理论和实验依据。 |
| 关键词: 刺五加 中枢神经系统 化学成分 药理作用 临床应用 |
| DOI：10.3969/j.issn.1674-070X.2018.08.028 |
| Received:November 24, 2017 |
| 基金项目:国家自然科学基金资助项目（81001657）；江苏省大学生创新创业训练计划（201712688001Y）。 |
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| Active Ingredients, Pharmacological Actions, and Clinical Applications of Acanthopanax senticosus in the Central Nervous System |
| ZHOU Lei,WANG Mengnan,ZHU Xiao,CHENG Huimin,WANG Yuxin,DU Fan,GUO Lengqiu |
| (College of Pharmacy, Suzhou Vocational Health College, Suzhou, Jiangsu 215000, China) |
| Abstract: |
| This paper reviews the research literature about the effect of Acanthopanax senticosus on the central nervous system all over the world in the last decade and reveals that the main active ingredients of Acanthopanax senticosus for the central nervous system are saponins and flavonoids. For the central nervous system, Acanthopanax senticosushas several clinical applications, including improving sleep quality, enhancing learning and memory, anti-depression, and anti-Parkinson. However, the mechanism of the effect of Acanthopanax senticosuson various nervous system diseases remains elusive. This paper provides theoretical and experimental evidence for the clinical applications of Acanthopanax senticosus in the central nervous system. |
| Key words: Acanthopanax senticosus central nervous system chemical constituents pharmacological action clinical application |
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