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袁春云,袁思斯.艾斯西酞普兰联合归脾汤治疗老年躯体形式障碍的临床观察[J].湖南中医药大学学报英文版,2018,38(8):921-924.[Click to copy
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| 艾斯西酞普兰联合归脾汤治疗老年躯体形式障碍的临床观察 |
| 袁春云,袁思斯 |
| (湖南省中医药研究院附属医院, 湖南 长沙 410006) |
| 摘要: |
| 目的 探究艾斯西酞普兰联合归脾汤治疗老年躯体形式障碍的临床疗效。方法 采用随机数字表法将50例老年躯体形式障碍患者分为艾斯西酞普兰组和艾斯西酞普兰+归脾汤组，每组各25例，各组分别给予相应的药物治疗6周。治疗前后观察各组治疗前后SCL-90、HAMD、GQOLI-74的评分及药物不良反应。结果 艾斯西酞普兰+归脾汤组的临床症状：躯体化、强迫症状、人际敏感、焦虑得到大幅度的改善，与艾斯西酞普兰组相比，差异有统计学意义（P<0.05或P<0.01）；HAMD评分、临床疗效结果、GQOLI-74评分显示艾斯西酞普兰+归脾汤组可明显提高显效率和生活质量，尤其对躯体功能与物质生活的改善幅度大，与单用艾斯西酞普兰治疗相比，差异有统计学意义（P<0.05或P<0.01）；艾斯西酞普兰+归脾汤组出现的不良反应明显少于艾斯西酞普兰组。结论 艾斯西酞普兰合用归脾汤可显著提高老年躯体形式障碍的显效率，改善临床症状和减少不良反应，提高生活质量。 |
| 关键词: 老年躯体形式障碍 艾斯西酞普兰 归脾汤 |
| DOI：10.3969/j.issn.1674-070X.2018.08.019 |
| Received:April 25, 2018 |
| 基金项目:湖南省自然科学基金项目（2016JJ6084）。 |
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| Clinical Efficacy of Escitalopram Combined with Guipi Decoction in Elderly Patients with Somatoform Disorders |
| YUAN Chunyun,YUAN Sisi |
| (The Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha 410006, Hunan, China) |
| Abstract: |
| Objective To investigate the clinical efficacy of escitalopram combinedwith Guipi Decoction in the treatment of elderly patients with somatoformdisorders. Methods Fifty elderly patients with somatoform disorders were randomly and equally divided into escitalopram group and escitalopram+Guipi Decoction group using a random number table.The patients were treated with corresponding drugs for 6 weeks.The scores for SCL-90, HAMD, and GQOLI-74 and adverse reactions were observed before and after treatment. Results The escitalopram+Guipi Decoction group had significantly greater improvements in somatization, obsessive-compulsive symptoms,interpersonal sensitivity, and anxiety than the escitalopram group (P<0.05 or P<0.01). According to the scores for HAMD and GQOLI-74 as well as the clinical treatment outcomes, the escitalopram+ Guipi Decoction group hadsignificantly greater improvements in marked response rate and the quality of life,particularly in body function and physical life, than the escitalopram group (P<0.05 or P<0.01). The escitalopram+Guipi Decoction group also hadsignificantly less adverse reactions than the escitalopram group. Conclusion Escitalopram combined with Guipi Decoction can significantly elevate the marked response rate, relieve clinical symptoms, reduce adverse reactions, and improve the quality of life. |
| Key words: elderly patients with somatoform disorders escitalopram Guipi Decoction |
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