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桂万弟,宋香清,李怡,金兰英.复方万年青胶囊联合美施康定治疗97例肺癌重度疼痛患者的临床观察[J].湖南中医药大学学报英文版,2017,37(12):1408-1413.[Click to copy
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| 复方万年青胶囊联合美施康定治疗97例肺癌重度疼痛患者的临床观察 |
| 桂万弟,宋香清,李怡,金兰英 |
| (武汉市江夏区第一人民医院内科, 湖北 武汉 430200;湖南省肿瘤医院药学部, 湖南 长沙 410013;武汉市江夏区第一人民医院药剂科, 湖北 武汉 430200) |
| 摘要: |
| 目的 观察复方万年青胶囊联合美施康定（硫酸吗啡缓释片）控制肺癌重度疼痛的效果。方法 回顾性调查97例肺癌重度疼痛患者，随机分为2组，对照组47例，采用美施康定治疗；试验组50例，采用复方万年青胶囊联合美施康定治疗，观察2组的抗癌痛效果、美施康定的人均维持日剂量、生活质量改善情况及不良反应发生情况。结果 与对照组相比，试验组抗癌痛效果较优（P<0.05），美施康定的人均维持日剂量较小（P<0.05），生活质量改善更明显（P<0.05），毒副作用更小。结论 复方万年青胶囊联合美施康定治疗肺癌重度疼痛，能明显缓解癌痛，增强止痛效果，减轻不良反应，提高生活质量。 |
| 关键词: 复方万年青胶囊 美施康定 硫酸吗啡缓释片 肺癌 疼痛 |
| DOI：10.3969/j.issn.1674-070X.2017.12.026 |
| Received:May 29, 2016 |
| 基金项目: |
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| Clinical Observation of Wannianqing Capsules Combined with Morphine Sulfate Sustained-Release Tablets on 97 Cases of Lung Cancer Patients with Severe Pain |
| GUI Wangdi,SONG Xiangqing,Li Yi,JIN Lanying |
| (Department of Medicine, the First People's Hospital of Jiangxia District, Wuhan, Hubei 430200, China;Department of Pharmacy, Hunan Cancer Hospital, Changsha, Hunan 410013, China;Department of Pharmacy, the First People's Hospital of Jiangxia District, Wuhan, Hubei 430200, China) |
| Abstract: |
| Objective To study the pain relieving effect of Wannianqing capsules combined with morphine sulfate sustained-release tablets for lung cancer patients. Methods 97 cancer patients with severe pain for retrospective analysis were randomly divided into control group and experimental group. 47 patients of the control group were treated by morphine sulfate sustained-release tablets only. In experimental group, 50 patients were treated by morphine sulfate sustained-release tablets combined with Wannianqing capsules. The analgesic effect, average daily dose of morphine sulfate sustained-release tablets, quality of life and adverse reaction in the two groups were observed. Results Compared with the control group, the experimental group had a better analgesic effect (P<0.05), a lower daily dose of morphine sulfate sustained-release tablets (P<0.05), more obvious improvement quality of life (P<0.05) and a lower adverse reactions incidence. Conclusion Wannianqing capsules combined with morphine sulfate sustained-release tablets can significantly relieve the pain, enhance the analgesic effect, alleviate the adverse reaction and improve the quality of life in treating lung cancer patients with severe pain. |
| Key words: Wannianqing capsules MS contin morphine sulfate sustained-release tablets lung cancer pain |
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