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李力,徐照,吉康生,吴春叶,刘静.复方穿山龙颗粒治疗类风湿性关节炎临床观察[J].湖南中医药大学学报英文版,2017,37(6):646-648.[Click to copy
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| 复方穿山龙颗粒治疗类风湿性关节炎临床观察 |
| 李力,徐照,吉康生,吴春叶,刘静 |
| (解放军第二五四医院中医免疫风湿科, 天津 300142;江西赣州上犹县中医院, 江西 赣州 341200) |
| 摘要: |
| 目的 观察复方穿山龙颗粒治疗类风湿性关节炎的临床疗效及不良反应。方法 将68例类风湿性关节炎患者随机分为治疗组（34例）和对照组（34例），治疗组给予复方穿山龙颗粒，对照组给予来氟米特片和洛索洛芬钠片，疗程3个月。观察两组临床疗效以及血沉（ESR）、C-反应蛋白（CRP）、类风湿因子（RF）的变化。结果 治疗组临床疗效的总有效率为85.3%，ESR、CRP、RF较治疗前均明显降低（P<0.05），与对照组比较差异无统计学意义（P>0.05），但不良反应发生率明显低于对照组，差异有统计学意义（P<0.05）。结论 复方穿山龙颗粒治疗类风湿性关节炎具有疗效确切、不良反应少等优点，适合患者较长时间服用。 |
| 关键词: 类风湿性关节炎 复方穿山龙颗粒 临床观察 |
| DOI：10.3969/j.issn.1674-070X.2017.06.018 |
| Received:January 26, 2016 |
| 基金项目: |
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| Clinical Effect of Compound Chuanshanlong Granule in the Treatment of Rheumatoid Arthritis |
| LI Li,XU Zhao,JI Kangsheng,WU Chunye,LIU Jing |
| (Department of TCM Immune Rheumatism, Hospital of PLA No. 254, Tianjin 300142, China;Shangyou County Hospital of TCM, Ganzhou, Jiangxi 341200, China) |
| Abstract: |
| Objective To observe the clinical efficacy and adverse reactions of compound Chuanshanlong granule in treatment of rheumatoid arthritis. Methods 68 cases of patients with rheumatoid arthritis were randomly divided into treatment group (34 cases) and control group (34 cases), the treatment group was given compound Chuanshanlong particles and the control group was administrated with leflunomide tablets and loxoprofen sodium tablets, the course was for three months. The clinical effect and erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF) were observed. Results The total effective rate in treatment group was 85.29%, ESR, C-reactive protein and rheumatoid factor were significantly lower than before treatment, compared with control group, the difference was not statistically significant (P>0.05), but the incidence of adverse reactions was significantly lower than the control group, the difference was statistically significant (P<0.05). Conclusion Compound Chuanshanlong granule has the advantages of definite curative effect, less adverse reactions. Patients could take it over a long period. |
| Key words: rheumatoid arthritis compound Chuanshanlong granule clinical observation |
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