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蒋晓煌,蒋孟良,贺卫和,李红,曾婷,何坪欣,赵新昱,张彪彪,赵梓含,邓潇潇.胶艾汤不同炮制组方对动物激素水平与凝血机制的影响[J].湖南中医药大学学报英文版,2017,37(6):591-593.[Click to copy
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| This paper
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| 胶艾汤不同炮制组方对动物激素水平与凝血机制的影响 |
| 蒋晓煌,蒋孟良,贺卫和,李红,曾婷,何坪欣,赵新昱,张彪彪,赵梓含,邓潇潇 |
| (湖南中医药大学, 湖南 长沙 410208) |
| 摘要: |
| 目的 优选胶艾汤的最佳炮制组方。方法 对胶艾汤全方生品、部分炮制、全方炮制a、全方炮制b等四种不同的炮制组合方进行大鼠激素水平与凝血机制的测定，比较不同炮制组方的药效活性。结果 胶艾汤对大鼠雌二醇、孕酮、睾丸酮、内皮素与6-酮-前列腺素F1α、血栓素B2作用强弱顺序是全方炮制b > 全方炮制a > 部分炮制 > 全方生品。结论 胶艾汤全方炮制b的止血作用最强。 |
| 关键词: 胶艾汤 中药炮制 雌二醇 孕酮 睾丸酮 内皮素 6-酮-前列腺素F1α 血栓素B2 |
| DOI：10.3969/j.issn.1674-070X.2017.06.003 |
| Received:August 06, 2016 |
| 基金项目:湖南省自然科学基金资助项目（14JJ2107）。 |
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| Effects of Jiaoai Decoction with Different Processing Methods on Hormone and Clotting Mechanism of Animals |
| JIANG Xiaohuang,JIANG Mengliang,HE Weihe,LI Hong,ZENG Ting,HE Pingxin,ZHAO Xinyu,ZHANG Biaobiao,ZHAO Zihan,DENG Xiaoxiao |
| (unan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective To optimize processing method of Jiaoai decoction. Methods The effects of Jiaoai decoction with four different methods, all crude drugs, part proccesing drugs, all drugs processing a, all drugs processing b, on hormone and clotting mechanism in rats were compared. Results The effects order of Jiaoai decoction on estradiol, progesterone, testosterone, ET, 6-Keto-PGF1α and TXB2 of rats was all drugs processing b > all drugs processing a > part proccesing drugs > all crude drugs. Conclusion The hemostatic effect of all drugs processing b in Jiaoai decoction was the strongest. |
| Key words: Jiaoai decoction Chinese crude drug processing estradiol progesterone testosterone ET 6-Keto-PGF1α TXB2 |
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