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李冉.小儿牛黄清心散对热性惊厥后脑损伤保护作用的临床研究[J].湖南中医药大学学报英文版,2017,37(2):216-219.[Click to copy
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| 小儿牛黄清心散对热性惊厥后脑损伤保护作用的临床研究 |
| 李冉 |
| (泰山医学院附属莱芜医院, 莱芜市人民医院儿科, 山东 莱芜 271100) |
| 摘要: |
| 目的 探讨小儿牛黄清心散对热性惊厥后脑损伤的保护作用。方法 将74例复杂性热性惊厥患儿随机分为治疗组40例和对照组34例，均予以常规治疗，治疗组加用小儿牛黄清心散口服，疗程14 d。比较两组治疗前后血清神经元特异性烯醇化酶（NSE）水平及脑电图异常率。结果 治疗后治疗组血清NSE水平恢复情况优于对照组（P<0.05）；脑电图异常率也显著低于对照组（P<0.05）。结论 小儿牛黄清心散治疗热性惊厥后脑损伤有明显疗效，且安全性良好。 |
| 关键词: 热性惊厥 脑损伤 小儿牛黄清心散 神经元特异性烯醇化酶 |
| DOI：10.3969/j.issn.1674-070X.2017.02.027 |
| Received:November 05, 2016 |
| 基金项目: |
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| Neuroprotective Effects of Xiaoer Niuhuang Qingxin Powder on Febrile Seizures Induced Brain Injury |
| LI Ran |
| (Department of Pediatrics, Laiwu People's Hospital, Laiwu Hospital Affiliated to Taishan Medical College, Laiwu, Shandong 271100, China) |
| Abstract: |
| Objective To explore the neuroprotective effects of Xiaoer Niuhuang Qingxin powder on febrile seizures induced brain injury. Methods Totally 74 patients with complex febrile seizures were randomly assigned into the treatment group (40 cases) and the control group (34 cases). Both groups were treated with routine therapy, while the treatment group was additionally given oral Xiaoer Niuhuang Qingxin powder, 14 d of one course. The serum neuron specific enolase (NSE) level and abnormal rate of electroencephalogram were compared before and after treatment. Results After treatment, the serum NSE level of treatment group was better than control group (P<0.05), and the abnormal rate of electroencephalogram was also significantly lower than control group. Conclusion Xiaoer Niuhuang Qingxin powder in treating febrile seizures induced brain injury shows good effect and safety. |
| Key words: febrile seizures brain injury Xiaoer Niuhuang Qingxin powder neuron specific enolase |
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