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谌海军1，谢梦洲1*，曾柏荣2，瞿昊宇1,贺 妍1，陈雪锋1，王理槐2.肺癌病性证素分布规律及其与血液检测指标关系的研究[J].湖南中医药大学学报英文版,2015,35(9):48-51.[Click to copy
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| 肺癌病性证素分布规律及其与血液检测指标关系的研究 |
| 谌海军1，谢梦洲1*，曾柏荣2，瞿昊宇1,贺妍1，陈雪锋1，王理槐2 |
| (1.湖南中医药大学，湖南 长沙 410208;2.湖南中医药大学第一附属医院，湖南 长沙 410007) |
| 摘要: |
| 目的 初步探讨肺癌病性证素的分布特点，为肺癌中医研究提供参考依据。 方法 采用临床回顾性研究，运用"中医智能(辅助)诊疗系统"进行系统辨证，采用SPSS 19.0统计软件对病性证素及血液检测指标进行统计。结果 肺癌病性证素以阴虚、气虚、饮、痰多见，不同病性证素分级以I、II级较常见。红细胞下降是血虚的危险因素(OR值=2.97>1)，CA125降低是血瘀的危险因素(OR值=10.908>1)，CEA降低是血瘀形成的抑制因素(OR值=0.267<1)，红细胞减少是痰、热病理变化形成的抑制因素(OR值=0.412、0.295<1)，CA125降低是饮形成的抑制因素(OR值=0.376<1)。结论 肺癌的病性证素以虚性证素为主，虚实夹杂，其中虚性病性证素以阴虚、气虚为主，实性病性证素主要为痰、热、饮及寒；随着红细胞的减少程度的增加，越容易出现血虚证素的病理变化，去越不容易出现痰、热证素的病理变化；CA125降低可能加速血瘀、减慢饮病理变化的形成；CEA的降低可能减慢血瘀的形成。 |
| 关键词: 肺癌 病性 证素 辨证 |
| DOI： |
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| 基金项目:中医诊断国家重点学科开放基金(2014-29，2013ZYZD06,2013ZYZD187）；湖南中医药大学中医诊断重点学科，湖南中医药大学中医诊断重点实验室资助。 |
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| Study of Syndrome Factors Distribution Rule of Lung Cancer and its Relationship with Blood Test Indicators |
| Hai-Jun Chen1, Meng-Zhou Xie1*, Bai-Rong Zeng2, Hao-Yu Qu1, Yan He1, Xue-Feng Chen1, Li-Huai Wang2 |
| (1. Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;2. The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Objective To investigate the distribution characters of lung cancer syndrome elements, and to provide a reference for lung cancer research of Chinese medicine. Methods The systematic dialectics were carried by using retrospective clinical study and “Chinese Intelligence (secondary) treatment system”. The syndrome elements and patient-related blood test indicators were analyzed by SPSS 19.0 statistical software. Results Common disease properties of lung cancer were: Yin deficiency, Qi deficiency, drink and phlegm. While different disease resistance syndrome element classification with I, II level were more common. Red blood cells reduce the risk factors for the disease of blood deficiency (OR value = 2.97>1), CA125 reduce is the risk factors of blood stasis (OR value = 10.908>1), reduced CEA is the disincentive of blood stasis (OR value = 0.267<1), red blood cells reduce is the disincentive of phlegm and heat (OR value = 0.412,0.295<1), CA125 lower is a disincentive for the formation of drink (OR value = 0.376 <1). Conclusion The pathological changes in the main deficiency of lung cancer with mixed excessiveness and deficiency. The deficiency syndromes were known for Yin deficienc and Qi deficiency, and solid venereal syndrome elements were mainly for phlegm, heat, drink and cold. With the large reduce of red blood cells, pathological changes of blood deficiency appeared easily, while the pathological changes of phlegm and heat syndrome factors were less prone to present. CA125 lower may speed up blood stasis and slow down the information of dink pathological changes. Lower CEA may reduce the formation of blood stasis. |
| Key words: lung cancer disease properties syndrome factors syndrome differentiation |
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