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Quote : 史晓岚; 杨帅; 王元惠; 张国庆; 何金森;.针药三种不同疗法对围绝经期抑郁症患者血清性激素及白介素-6的影响[J].湖南中医药大学学报英文版,2012,32(11):70-73.[Click to copy ]
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针药三种不同疗法对围绝经期抑郁症患者血清性激素及白介素-6的影响
史晓岚;杨帅;王元惠;张国庆;何金森;
(上海市江湾医院中医科; 上海市江湾医院统计信息科; 上海中医药大学针推学院)
摘要:
    目的比较电针、中药、针药结合3种不同疗法对围绝经期抑郁症的血清性激素及IL-6的影响。方法将确诊为围绝经期抑郁症的患者随机分为电针组、中药组和针药结合组,电针组采用电针治疗的方法,中药组采用中药汤剂口服,针药结合组采用上述两种治疗相结合的方法。治疗1个月后观察其血清雌二醇(E2)、促黄体生成素(LH)、卵泡刺激素(FSH)及血清白介素-6(IL-6)的含量。结果 3组E2治疗前后比较(P<0.05),差异具有统计学意义;LH、FSH治疗前后比较(P>0.05),差异无统计学意义;IL-6含量治疗前后比较(P<0.05),差异具有统计学意义。结论 3种疗法均能升高围绝经期抑郁症患者血清E2的含量,并使血清IL-6的含量有一定程度的下降,说明围绝经期抑郁症患者症状的改善可能与E2、IL-6相关。 更多还原
关键词:  围绝经期抑郁症  针灸  电针  中药  血清性激素  白介素-6  临床观察  
DOI:
  
基金项目:上海市卫生局中医药科研课题资助项目(2008L019A)
Effects of electro-acupuncture and herbal medicine and the cimbined treatment on serum sex hormones and interleukin 6 of patients with peri-menopausal period depression
SHI Xiao-lan1,YANG Shuai1,WANG Yuan-hui1,ZHANG Guo-qing2,HE Jin-sen3
(1.Department of Chinese Medicine,Shanghai Jiangwan Hospital,Shanghai 200434,China; 2.Department of Statistics and Information,Shanghai Jiangwan Hospital,Shanghai 200434,China; 3.College of Acupuncture and Moxibustion,TCM University of Shanghai,Shanghai 201203,China)
Abstract:
    〔Abstract〕Objective To analyze and compare the effects of 3 different treatments of electroacupuncture, herbal medicine and combined electro -acupuncture and herbal medicine on serum sex hormones and interleukin 6 (IL-6) in treating perimenopausal period depression. Methods Patients with perimenopausal period depression were randomly divided into 3 groups, electro-acupuncture group, herbal medicine group and combined treatment group. The treatment course of 3 groups was 1 month. The serum estradiol(E2), luteinizing hormone(LH), follicle stimulating hormone(FSH) and IL-6 were tested and compared among groups. Results Before and after treatment, the E2 and IL-6 level of 3 groups showed statistical significance (P<0.05) while LH, FSH levels of 3 groups showed no statistical significance(P>0.05). Conclusion 3 treatment methods can increase the E2 levelof patients with perimenopausal period depression. On the contrary, IL-6 levels have a certain degree of decline after treatments. The mechanism of improving perimenopausal period depression is probably relatd to E2 and IL-6.
Key words:  perimenopausal period depression  acupuncture  electro -acupuncture  Chinese herbal medicine  serum sex hormones  IL-6  clinical observation
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