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郑毅春1，盛丹2，朱照平1，何天文1.滋阴清热法治疗男性不育症的临床观察[J].湖南中医药大学学报英文版,2012,32(7):58-60.[Click to copy
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| 滋阴清热法治疗男性不育症的临床观察 |
| 郑毅春1，盛丹2，朱照平1，何天文1 |
| (1．广东省妇幼保健院 2．四川泸州医学院) |
| 摘要: |
| 目的观察滋阴清热法对男性不育症阴虚湿热证的临床疗效。方法选择60 例中医辨证为阴虚湿热证的
男性不育症患者，采用滋阴清热法治疗，并与西药对照组56 例患者进行比较，对治疗前后的精液不液化疗效、精子活
力、正常形态精子率、慢性前列腺炎NIH-CPSI 评分、精浆白介素－6（IL-6）、肿瘤坏死因子（TNF-α）等方面进行比较。
结果治疗组对精液不液化疗效优于对照组（P＜0.01）；治疗组治疗后精子活力、正常形态精子率明显提高，优于对照组
（P＜0.01)；治疗组精浆IL-6、TNF-α 含量明显降低，与对照组比较差异有统计学意义（P＜0.01）；治疗组慢性前列腺炎
NIH-CPSI 评分明显降低，与对照组比较差异有统计学意义（P＜0.05)。结论滋阴清热法能促进精液液化，提高精子活
力，调整细胞因子功能，降低炎症反应，促进前列腺的分泌功能。 |
| 关键词: 男性不育症 滋阴清热法 阴虚湿热 中医药疗法 |
| DOI： |
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| 基金项目:广东省中医药管理局资助项目（3034118）。 |
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| Clinical effects of nourishing Yin and clearing heatmethods on male infertility |
| ZHENG Yi-chun1, SHENG Dan2, ZHU Zhao-ping1, HE Tian-wen1 |
| (1. Guangdong Hospital for Women’s and Children’s Healthcare 2. Luzhou Medical College) |
| Abstract: |
| Objective To observe the therapeutic efficacy of nourishing Yin and clearing heat methods
on male infertility with deficiency of Yin and damp-heat syndrome. Methods 60 male infertility
patients with TCM deficiency of Yin and damp -heat syndrome were treated with nourishing Yin
and clearing heat methods as the treatment group. 56 patients were treated with Western Medicine
as the control group. Before and after treatments, comparative study between 2 groups was conducted
on the indexes of semen liquefaction efficacy, sperm motility, normal sperm morphology rate, chronic
prostatitis NIH-CPSI score, seminal plasma IL-6 and TNF-α. Results The treatment group had better
therapeutic efficacy in semen nonliquefaction disease than the control group（P＜0.01）. After treatments,
sperm motility and normal sperm morphology rate were improved significantly in treatment
group and the efficacy was higher than that of the control group （P ＜0.001). Compared
with control group, seminal plasma IL -6 and TNF -α contents were significantly lower in treatment
group after treatments; there were significant statistic differences （P ＜0.001）. Compared
with control group, chronic prostatitis NIH-CPSI score was significantly reduced in treatment group
after treatments; there were significant statistic differences （P ＜0.05）. Conclusion Nourishing Yin
and clearing heat methods can promote semen liquefaction, increase sperm motility, adjust
the cytokine functions, reduce inflammation and promote prostate secretion. |
| Key words: male infertility nourishing Yin and clearing heat methods deficiency of Yin
and damp-heat syndrome Traditional Chinese Medical therapy |
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