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彭伟军，邢之华 廖翔，刘卫平.益气活血法对冠心病稳定型心绞痛气虚血癖证
患者血清IL-6,TNF-。及ICAIVI-1的影响[J].湖南中医药大学学报英文版,2011,31(7):49-51.[Click to copy
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| 益气活血法对冠心病稳定型心绞痛气虚血癖证
患者血清IL-6,TNF-。及ICAIVI-1的影响 |
| 彭伟军，邢之华廖翔，刘卫平 |
| ((中南大学湘雅医院中西医结合研究所，湖南长沙410008)) |
| 摘要: |
| 〔摘要〕目的观察益气活血之保心汤对气虚血疲型冠心病稳定型心绞痛患者的疗效及对血清白介素一6 ( IL-
6)、肿瘤坏死因子一。(TNF-a)、细胞间粘附分子一1(ICAM-1)的影响〔方法60例患者随机分为治疗组和对照组，分
别采用保心汤和西药治疗4周后，观察两组治疗心绞痛的疗效和患者治疗前后血清IL-6 ,TNF-a ,ICAM-1水平的
变化〔结果治疗组疗效评价明显优于对照组((P<0.05) ;治疗组患者治疗后血清IL-6 ,TNF-a ,ICAM-1水平较治疗前
明显降低(P<0.01)结论保心汤对气虚血疲型冠心病心绞痛患者有确切的疗效，可能通过抑制血清IL-6,TNF-a,
TCAM-1 iK平_从而抑制}h'}}应_以iJ.- }}I疗冠心病}.} }.h 'J ,I`} }u痛的作用. |
| 关键词: 冠心病稳定型心绞痛 益气活血法 相关炎症因子 |
| DOI： |
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| 基金项目:湖南省科技厅科技计划资助项日(08SK3130) |
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| Effectof YiqiTNF-aHuoxue therapyon serumIL-6, ICAM-1patients with stable angina pectorisdeficiency and blood stasisn .1.，qandm |
| PENG Wei一un, XING Zhi-hua, LIAO Xiang, LIU Wei-ping |
| ((Institute of Integrated Chinese and Western Medicine, Xiangya Hospital, Central South Universi-
ty, Changsha, Hunan, 410008, China)) |
| Abstract: |
| (Abstract〕 Objective To investigate the effects of Baoxin decoction on serum IL-6, ICAM-
1 and TNF -cx in patients with stable angina pectoris. Methods 60 patients were random-
1y divided into treatment group treated with Baoxin decoction and control group treated with rou-
tine treatments. The curative effects in lx>th groups and the levels of serum IL-6, ICAM一1 and
TNF-cx were measured before treatment and after 4 weeks therapy. Results The curative effects
in treatment group was much better than that in control group(P<0.05), the levels of serum IL-6,
TNF-cx and ICAM一1 in treatment group after treatment were obviously decreased (P<0.01). Con-
elusion Baoxin decoction is exact effective[()cure coronary heart disease with stable angina
pectoris, and the mechanism may be through inhibiting the levels of serum IL-6, ICAM一1 and
TNF-cx and decreasing the inflammation reaction. |
| Key words: stable angina pectoris Yiqi Huoxue therapy related inflammatory molecules |
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