| 引用本文: |
杨月华, 林燕.基于“虚-滞-积”动态演变探讨糖尿病肾病的病机与治疗[J].湖南中医药大学学报,2025,45(6):1111-1116[点击复制] |
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| 基于“虚-滞-积”动态演变探讨糖尿病肾病的病机与治疗 |
| 杨月华,林燕 |
| (天津中医药大学第一附属医院, 国家中医针灸临床医学研究中心, 天津 300382) |
| 摘要: |
| 糖尿病肾病是糖尿病常见的并发症，属于中医学“消渴肾病”范畴。中医药在治疗糖尿病肾病方面有独特疗效，明确其病机对于指导临床具有重要意义。糖尿病肾病病机多属本虚标实，“虚-滞-积”的病机转化规律符合糖尿病肾病由虚至实的病变基础。糖尿病肾病以脾肾亏虚为主，气机紊乱，阻滞脉络，进而积聚各种病理产物，损伤络脉，导致疾病进入终末期。治疗上针对病机，分期论治，合理兼筹补益脾肾、调畅气机、清热利湿、活血化瘀、解毒泄浊等治法，从而为糖尿病肾病提供最佳的治疗方案。 |
| 关键词: 糖尿病肾病 虚-滞-积 动态演变 理论探讨 辨证论治 |
| DOI：10.3969/j.issn.1674-070X.2025.06.019 |
| 投稿时间：2025-01-10 |
| 基金项目:国家自然科学基金面上项目（81373609）。 |
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| Pathogenesis and treatment of diabetic nephropathy based on the dynamic evolution of "deficiency-stagnation-accumulation" |
| YANG Yuehua, LIN Yan |
| (First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300382, China) |
| Abstract: |
| Diabetic nephropathy is a common complication of diabetes mellitus and belongs to the category of wasting and thirst disorders in TCM. Chinese medicine has unique efficacy in the treatment of diabetic nephropathy, and it is important to clarify the disease mechanism to guide clinical treatment. The pathogenesis of diabetic nephropathy is often characterized as a combination of deficiency at the root and excess in the manifestation. The transformation pattern of “deficiency-stagnation-accumulation” corresponds to the pathological basis of this disease progressing from deficiency to excess. Diabetic nephropathy mainly involves deficiency of spleen and kidney, leading to disordered qi stagnating in the meridians and collaterals which in turn Results in accumulation of various pathological products and damage to collaterals. These factors lead the disease into its terminal stage. In terms of treatment, therapeutic strategies should be tailored to the underlying pathogenesis, with staged interventions that appropriately combine the Methods such as tonifying the spleen and kidney, regulating qi, clearing heat and draining dampness, circulating blood and transforming stasis, and removing toxins and eliminating turbidity. This comprehensive approach aims to provide the optimal treatment plan for diabetic nephropathy. |
| Key words: diabetic nephropathy deficiency-stagnation-accumulation dynamic evolution theoretical discussion pattern identification and treatment |
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