| 引用本文: |
张宜帆, 罗晓欣, 钟燕, 柏雅楠, 孔炜明, 简维雄.基于“阴阳自和”理论探讨线粒体功能障碍对血管衰老的影响[J].湖南中医药大学学报,2025,45(1):105-109[点击复制] |
|
| |
|
|
| 本文已被：浏览 646次 下载 212次 |
| 基于“阴阳自和”理论探讨线粒体功能障碍对血管衰老的影响 |
| 张宜帆,罗晓欣,钟燕,柏雅楠,孔炜明,简维雄 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学国家重点学科中医诊断学湖南省重点实验室, 湖南 长沙 410208) |
| 摘要: |
| 血管衰老是多种老年慢性疾病的基础病理过程，而线粒体功能障碍在其发生发展中起关键作用。线粒体的动态调节过程，包括分裂与融合、自噬与生物合成，体现了中医学“阴阳自和”理论中阴阳对立统一与相互转化的观点。文章从“阴阳自和”理论角度出发，探讨线粒体功能障碍在血管衰老中的作用机制，阐明阴阳平衡在维持线粒体功能和血管衰老中的关键作用，旨在为血管衰老的预防和治疗提供理论支持和实践依据。 |
| 关键词: 阴阳自和 线粒体 稳态 血管衰老 线粒体功能障碍 |
| DOI：10.3969/j.issn.1674-070X.2025.01.015 |
| 投稿时间：2024-08-02 |
| 基金项目:国家自然科学基金项目((82374334);湖南省自然科学基金项目(2022JJ30433);湖南中医药大学研究生创新课题(2024CX038)。 |
|
| Effects of mitochondrial dysfunction on vascular aging based on the theory of "spontaneous harmonization between yin and yang" |
| ZHANG Yifan, LUO Xiaoxin, ZHONG Yan, BO Yanan, KONG Weiming, JIAN Weixiong |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Key Laboratory of Chinese Medicine Diagnostics, National Key Discipline of Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Vascular aging is a fundamental pathological process underlying various chronic diseases in the elderly, with mitochondrial dysfunction playing a critical role in its occurrence and progression. The dynamic regulation process of mitochondria,including fission and fusion, autophagy and biosynthesis, embodies the view of the opposing unity and mutual transformation of yin and yang in the theory of “spontaneous harmonization between yin and yang” in Chinese medicine. Starting from the perspective of“spontaneous harmonization between yin and yang” theory, this article explores the mechanisms of action of mitochondrial dysfunction in vascular aging and clarifies the key role of yin and yang balance in maintaining mitochondrial function and vascular aging. It aims to provide theoretical support and practical basis for the prevention and treatment of vascular aging. |
| Key words: spontaneous harmonization between yin and yang mitochondria homeostasis vascular aging mitochondrial dysfunction |
|
二维码（扫一下试试看！） |
|
|
|
|
