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杨霄,闫小宁,蔺莉,张书婵.基于数据挖掘探析韩世荣教授治疗慢性荨麻疹的用药规律[J].湖南中医药大学学报,2022,42(4):665-670[点击复制] |
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| 基于数据挖掘探析韩世荣教授治疗慢性荨麻疹的用药规律 |
| 杨霄,闫小宁,蔺莉,张书婵 |
| (陕西中医药大学, 陕西 咸阳 712046;陕西省中医医院皮肤科, 陕西 西安 710003) |
| 摘要: |
| 目的 利用数据挖掘，分析探讨韩世荣教授治疗慢性荨麻疹的用药经验。方法 基于中医传承辅助平台（V2.5）软件，收集韩世荣教授治疗慢性荨麻疹的门诊病案，并将数据录入此软件，对录入的处方进行四气五味统计、药物频次统计、关联规则分析、复杂系统熵聚类等数据挖掘，分析用药规律。结果 共纳入121个处方，涉及113味中药，使用频次较高的药物有地肤子、荆芥、防风、蝉蜕、白鲜皮、浮萍、当归等；药性以寒、温、平为主，而药味以甘、辛、苦为主，归经以脾、肺、肝、胃为主；常用药对有“荆芥-防风”“荆芥-地肤子”“蝉蜕-地肤子”“防风-地肤子”等；聚类分析得出新方4首，功效以疏风清热解表、养血理气、燥湿止痒为主。结论 韩教授认为内外风邪是慢性荨麻疹发病的关键点，肺脾之气受损，气虚无以运血，且久病内耗阴血，血虚生风，复因外受风邪等发病，治疗上以健脾补肺、益气活血为法，兼以清热祛湿、润燥祛风。 |
| 关键词: 慢性荨麻疹 韩世荣 中医药 名医经验 用药规律 |
| DOI：10.3969/j.issn.1674－070X.2022.04.024 |
| 投稿时间：2021-04-20 |
| 基金项目:陕西省中医药管理局科研项目（2019-GJ-LC009）；创新人才推进计划-重点科技创新团队计划（2017KCT-27）。 |
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| Analysis of professor Han Shirong's medication rule in the treatment of chronic urticaria based on data mining |
| YANG Xiao,YAN Xiaoning,LIN Li,ZHANG Shuchan |
| (Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, China;Department of Dermatology, Shaanxi Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi 710003, China) |
| Abstract: |
| Objective To analyze professor Han Shirong's medication experience in treating chronic urticaria by data mining. Methods Based on the Chinese medicine inheritance assistant platform (V2.5) software, the outpatient medical records of professor Han Shirong in the treatment of chronic urticaria were collected, and the data were entered into this software, the input prescriptions were analyzed by data mining, such as the statistics of the four Qi and five flavors, statistics of drug frequency, association rule analysis, and complex system entropy clustering and so on. Results A total of 121 prescriptions were included, involving 113 traditional Chinese medicines. The most frequently used drugs were Difuzi (Kochiae Fructus), Jingjie (Schizonepetae Herba), Fangfeng (Saposhnikoviae Radix), Chantui (Cicadae Periostracum), Baixianpi (Dictamni Cortex), Fuping (Spirodelae Herba), Danggui (Angelicae Sinensis Radix) etc. The main properties were cold, warm, and flat, the main medicinal tastes were sweet, pungent, bitter, the main meridians were the spleen, lung, liver, and stomach. The commonly used drug combinations were Jingjie (Schizonepetae Herba)-Fangfeng (Saposhnikoviae Radix), Jingjie (Schizonepetae Herba)-Difuzi (Kochiae Fructus), Chantui (Cicadae Periostracum)-Difuzi (Kochiae Fructus), Fangfeng(Saposhnikoviae Radix)-Difuzi(Kochiae Fructus) etc. Cluster analysis revealed 4 new prescriptions, the main effects were to disperse wind, clear heat and relieve the surface, nourish blood and regulate Qi, dry dampness and relieve itching. Conclusion Professor Han believes that internal and external wind pathogens are the key points in the onset of chronic urticaria. The Qi of the lung and spleen is damaged, Qi deficiency is not able to transport blood, and the chronic illness consumes Yin blood, blood deficiency produces wind, and the disease is caused by external wind. The treatment is to invigorate the spleen, nourish the lung, replenish Qi and activate blood, and also to clear away heat and dispel dampness, moisturize dryness and dispel wind. |
| Key words: chronic urticaria Han Shirong traditional Chinese medicine famous doctor's experience medication rule |
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