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武子健,董鑫,赵炎,杜晓雪,金娟,刘莉.冠心病血瘀证与血液检验相关指标分析[J].湖南中医药大学学报,2019,39(2):230-233[点击复制] |
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| 冠心病血瘀证与血液检验相关指标分析 |
| 武子健,董鑫,赵炎,杜晓雪,金娟,刘莉 |
| (黑龙江中医药大学, 黑龙江 哈尔滨 150040;黑龙江中医药大学, 黑龙江 哈尔滨 150040;黑龙江中医药大学附属第一医院, 黑龙江 哈尔滨 150040) |
| 摘要: |
| 目的 探讨冠心病血瘀证与血液相关检验指标的关系。方法 选择175例冠心病患者，其中血瘀证组112例，非血瘀证组63例。研究对象均在住院次日清晨平躺测量血压，空腹状态下抽取静脉血液留置标本，检测血常规和血脂、血糖、肾功能等生化指标，记录患者吸烟史。比较两组患者指标的差异性。结果 血瘀证组患者的血常规中红细胞分布宽度-CV值（Rdw-cv）、红细胞分布宽度-SD值（Rdw-sd）、血小板分布宽度（Pdw）、血小板平均体积（Mpv）、血小板比积（Pct）、大型血小板比率（P-lct）均明显高于非血瘀证组（P<0.01，P<0.05）；血瘀证组患者载脂蛋白B（ApoB）、血脂总胆固醇（TC）均明显高于非血瘀证组（P<0.01，P<0.05）；血瘀证组中患者吸烟率明显高于非血瘀证组（P<0.05）。结论 冠心病血瘀证组患者Rdw-cv、Rdw-sd、Pdw、Mpv、Pct、P-lct、TC、ApoB及烟率均明显高于非血瘀证组，差异具有统计学意义，故以上指标可以作为冠心病血瘀证中医辨证分型的客观临床指标。 |
| 关键词: 冠心病 血瘀证 红细胞分布宽度 血小板参数 血脂 吸烟 |
| DOI：10.3969/j.issn.1674-070X.2019.02.019 |
| 投稿时间：2018-03-08 |
| 基金项目:中国博士后科学基金（2015M571452）；黑龙江省博士后科研启动基金（LBH-Z13194） |
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| Relationship Between Blood Stasis Syndrome and Related Blood Test Parameters in Coronary Heart Disease |
| WU Zijian,DONG Xin,ZHAO Yan,DU Xiaoxue,JIN Juan,LIU Li |
| (Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China;Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China) |
| Abstract: |
| Objective To investigate the relationship between blood stasis syndrome and related blood test parameters in coronary heart disease. Methods A total of 175 cases of coronary heart disease were enrolled in the study, which included 112 cases in the blood stasis syndrome group and 63 cases in the non-blood stasis syndrome group. The supine blood pressure was measured for all the subjects in the morning of the next day of hospitalization; their fasting venous blood samples were taken for routine blood test and related biochemical tests including blood lipids, blood glucose, and renal function; meanwhile, the smoking history of these patients was recorded. These indices were compared between the two groups. Results Compared with the non-blood stasis syndrome group, the blood stasis syndrome group had significantly higher values in the following routine blood test results: red blood cell distribution width-CV (RDW-CV), red blood cell distribution width-SD (RDW-SD), platelet distribution width (PDW), mean platelet volume (MPV), plateletcrit (PCT), and platelet-large cell ratio (P-LCR) (P<0.05， P<0.01), significantly higher levels of apolipoprotein B (ApoB) and total cholesterol (TC) (P<0.05 or P<0.01), and a significantly higher smoking rate (P<0.05). Conclusion RDW-CV, RDW-SD, PDW, MPV, PCT, P-LCR, TC, ApoB, and smoking rate are significantly higher in the blood stasis syndrome group of patients with coronary heart disease than in the non-blood stasis syndrome group. Therefore,he above indices can be used as objective clinical indices for the differentiation of blood stasis syndrome in patients with coronary heart disease. |
| Key words: coronary heart disease blood stasis syndrome red blood cell distribution width platelet parameter blood lipid smoking |
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