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贡钰霞,钱海华,谷云飞.大剂量生白术配伍枳实治疗慢传输型便秘62例[J].湖南中医药大学学报,2016,36(10):56-59[点击复制] |
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大剂量生白术配伍枳实治疗慢传输型便秘62例 |
贡钰霞,钱海华,谷云飞 |
(江苏省中医院, 江苏 南京 210046) |
摘要: |
目的 观察大剂量生白术配伍枳实治疗慢传输型便秘的临床疗效。方法 符合纳入标准的慢传输型便秘患者62例,采用大剂量生白术配伍枳实煎剂治疗,14 d为1个疗程,治疗2个疗程。分别记录治疗前、1个疗程后、2个疗程后及停药2周后患者便秘症状评分(CCS)及生活质量估量评分(PAC)。结果 治疗结束时,治愈31例,显效16例,有效10例,无效5例,总有效率91.9%。治疗1个疗程后、2个疗程后及停药2周后与治疗前对比,便秘症状(除腹痛)及生存质量均有显著改善(P<0.05);治疗2个疗程后、停药2周后与治疗1个疗程后对比,便秘症状(除腹痛与排便辅助方法)及生存质量均有显著改善(P<0.05)。结论 大剂量生白术配伍枳实能显著改善慢传输型便秘患者的临床症状及生活质量,临床疗效确切。 |
关键词: 慢传输型便秘 中医药疗法 生白术 枳实 临床观察 |
DOI:10.3969/j.issn.1674-070X.2016.10.015 |
投稿时间:2016-07-18 |
基金项目:国家自然科学基金资助项目(81573979)。 |
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Large Doses of Baizhu combined with Zhishi in Treating 62 Cases of Slow Transit Constipation Patients |
GONG Yuxia,QIAN Haihua,GU Yunfei |
(Jiangsu Hospital of TCM, Nanjing, Jiangsu 210046, China) |
Abstract: |
Objective To observe the clinical effect of large dose of white atractylodes rhizome (Baizhu) combined with fructus aurantii immaturus (Zhishi) on slow transit constipation (STC) patients.Methods The 62 cases of STC included in the standard,were treated with high dose of Baizhu combined with Zhishi decoction for 2 courses of treatment,14 days for one course.The constipation score and quality of life at before treatment,after one course of treatment,2 courses of treatment and 2 weeks after stopping drug were recorded,respectively.Results At the end of the therapy,31 cases were cured,16 cases had an obvious effect,10 cases had effect,5 cases had no effect.The total effective rate was 91.9%.The symptoms of constipation (except abdominal pain) and constipation-quality of life were improved obviously after one course of treatment,2 courses of treatment,2 weeks after stopping drug than before treatment (P<0.05).Compared with the effect of one course of treatment,the symptoms of constipation (except abdominal pain) and constipation-quality of life were improved obviously at 2 courses of treatment,2 weeks after stopping drug (P<0.05).Conclusion Large dose of Baizhu combined with Zhishi can improve symptoms and quality of life of STC patients obviously. |
Key words: slow transit constipation therapy of chinese medicine white atractylodes rhizome fructus aurantii immaturus clinical observation |
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