| 引用本文: |
吴彬才,杨柳,王莘智,吴鑫,旷惠桃.基于数据挖掘的旷惠桃教授治疗痛风用药规律研究[J].湖南中医药大学学报,2017,37(5):556-561[点击复制] |
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| 基于数据挖掘的旷惠桃教授治疗痛风用药规律研究 |
| 吴彬才,杨柳,王莘智,吴鑫,旷惠桃 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 目的 应用中医传承辅助系统软件分析旷惠桃教授治疗痛风（Gout）的用药及组方规律。方法 收集旷惠桃教授2015年9月-2016年5月治疗痛风部分病例，录入“中医传承辅助平台（V2.5）”系统，采用系统中的关联规则、改进互信息法、复杂系统熵聚类等无监督数据挖掘方法，探析旷教授治疗痛风的常用药物及分析方剂中的组方规律。结果 对纳入的69名患者，共198首处方、119味中药进行分析，使用频次>100次的高频使用药物有牛膝、土茯苓、车前子、萆薢、地龙、灵芝、威灵仙、黄柏、泽泻、黄芪；药物类别主要包括清热药、利湿药、活血通络药；常用药对包括：土茯苓-牛膝，土茯苓-萆薢，牛膝-萆薢，车前子-牛膝，车前子-土茯苓，车前子-萆薢等；挖掘旷惠桃教授治疗痛风的基本方及5首新处方。结论 旷惠桃教授临床善于运用清热、解毒、利湿之方药治疗痛风。 |
| 关键词: 痛风 中医传承辅助平台 清热 解毒 利湿 旷惠桃 |
| DOI：10.3969/j.issn.1674-070X.2017.05.025 |
| 投稿时间：2016-06-01 |
| 基金项目:国家中医药管理局“2014年全国名老中医药专家旷惠桃传承工作室建设项目”资助（国中医药人教发[2014]20号）。 |
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| Analysis on Medicine Law of Professor Kuang Huitao in Treating Gout Based on Data Mining Method |
| WU Bincai,YANG Liu,WANG Shenzhi,WU Xin,KUANG Huitao |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Objective To investigate the medication and prescription of professor Kuang Huitao on gout by traditional Chinese medicine inheritance system software. Methods Some cases of gout patients treated by Professor Kuang Huitao from September 2015 to May 2016 were colected, and data were inputed into the "heritage of traditional Chinese medicine auxiliary platform (V2.5)" system, then using the unsupervised data mining method in the system,such as association rules, the mutual information method, the entropy clustering method of complex system,etc. The laws on common drugs and prescription in treatment of gout were investigated. Results The most common used drugs (over 100 times) in 198 prescriptions including 119 herbs among 69 cases patients were radix achyranthis bidentatae (Niuxi), smilax glabra (Tufuling), plantago seed (Cheqianzi), poison yam (Bixie), lumbricus (Dilong), glossy ganoderma (Lingzhi), radix clematidis (Weilingxian), golden cypress (Huangbai), rhizoma alismatis (Zexie), astragalus mongholicus (Huangqi). The main categories of drugs include heat-clearing, dampness-disinhibiting, activating blood and dredging collaterals medicines. The common used couplet medicines are Tufuling-Niuxi, Tufuling-Bixie, Niuxi-Bixie, Cheqianzi-Niuxi, Cheqianzi-Tufuling, Cheqianzi-Bixie. The basic prescriptions and five new prescriptions for treatment of gout were explored. Conclusion The prescriptions of clearing heat, detoxification and removing dampness by Professor Kuang Huitao show good effect on gout. |
| Key words: gout traditional Chinese medicine inheritance support system clearing heat detoxication removing dampness Kuang Huitao |
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