| 引用本文: |
邱赛红,黄湘珺,黄宇明,黄拓.灵芝及其提取物减轻肝损伤作用的研究概况[J].湖南中医药大学学报,2017,37(4):461-464[点击复制] |
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| 灵芝及其提取物减轻肝损伤作用的研究概况 |
| 邱赛红,黄湘珺,黄宇明,黄拓 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学2014级硕士研究生班, 湖南 长沙 410208;湖南正清制药集团国际华人灵芝社, 湖南 长沙 410205) |
| 摘要: |
| 灵芝为古称的“九大仙药”之一，最早的中药典籍《神农本草经》中即有收载。灵芝中含有丰富的多糖、三萜类、肽类和核苷，是其所产生临床疗效的重要物质基础。本文对灵芝及其提取物在减轻肝损伤方面的研究文献进行了整理。研究显示，灵芝及其提取物对多种有毒物质及免疫与缺血等因素造成的肝损伤均有保护作用，并在抑制肝纤维化、减轻脂肪肝形成等方面也具有良好的作用趋势，可供灵芝在临床的应用及进一步研究与开发参考。 |
| 关键词: 灵芝 肝损伤 护肝 肝纤缩化 脂肪肝 |
| DOI：10.3969/j.issn.1674-070X.2017.01.032 |
| 投稿时间：2016-06-06 |
| 基金项目:湖南怀化市科技计划重大专项资助（S2016G501P00） |
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| Recent Advances in Ganoderma and its Constituents on Reducing Liver Damage |
| QIU Saihong,HUANG Xiangjun,HUANG Yuming,HUANG Tuo |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Postgraduate in Grade 2014, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Chinese Ganoderma Association, Changsha, Hunan 410205, China) |
| Abstract: |
| As one of the ancient "Nine Heaven-sent Medicine", ganoderma lucidum was included in China's first herbal medicine book, The Classic of Herbal Medicine. Today, we have a deeper understanding on this fungus. Ganoderma lucidum is rich in ganoderan, triterpenes, peptides and nucleosides, which is the foundation of the herb's clinical effectiveness. In this paper, the studies on ganoderma lucidum and its constituents in reducing liver damage were analyzed. Researches show that ganoderma lucidum and its extracts has a protective effect on liver damage caused by toxins, immunologic reasons and ischemia. Meanwhile, it also has positive effect on controlling hepatic fibrosis and alleviating hepatic lipidosis. It provides reference for the clinical application and further research of ganoderma lucidum. |
| Key words: ganoderma lucidum liver damage liver protection hepatic fibrosis fatty liver |
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